A Novel Splice Variant of the Masculinizing Gene Masc with piRNA-Cleavage-Site Defect Functions in Female External Genital Development in the Silkworm, Bombyx mori

In the silkworm, the sex-determination primary signal Fem controls sex differentiation by specific binding of Fem-derived piRNA to the cleavage site in Masc mRNA, thus inhibiting Masc protein production in the female. In this study, we identified a novel splicing isoform of Masc, named Masc-S, which...

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Detalles Bibliográficos
Autores principales: Zhao, Qin, Li, Juan, Wen, Mao-Yu, Wang, He, Wang, Yao, Wang, Kai-Xuan, Wan, Qiu-Xing, Zha, Xing-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723575/
https://www.ncbi.nlm.nih.gov/pubmed/31366115
http://dx.doi.org/10.3390/biom9080318

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