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Dietary Intake of Fatty Acids, Total Cholesterol, and Stomach Cancer in a Chinese Population

To investigate the associations between dietary fatty acids and cholesterol consumption and stomach cancer (SC), we analyzed data from a population-based case-control study with a total of 1900 SC cases and 6532 controls. Dietary data and other risk or protective factors were collected by face-to-fa...

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Autores principales: Zhu, Yu-Hui, Jeong, Somee, Wu, Ming, Jin, Zi-Yi, Zhou, Jin-Yi, Han, Ren-Qiang, Yang, Jie, Zhang, Xiao-Feng, Wang, Xu-Shan, Liu, Ai-Ming, Gu, Xiao-Ping, Su, Ming, Hu, Xu, Sun, Zheng, Li, Gang, Li, Li-Ming, Mu, Li-Na, Lu, Qing-Yi, Zhao, Jin-Kou, Zhang, Zuo-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723637/
https://www.ncbi.nlm.nih.gov/pubmed/31357492
http://dx.doi.org/10.3390/nu11081730
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author Zhu, Yu-Hui
Jeong, Somee
Wu, Ming
Jin, Zi-Yi
Zhou, Jin-Yi
Han, Ren-Qiang
Yang, Jie
Zhang, Xiao-Feng
Wang, Xu-Shan
Liu, Ai-Ming
Gu, Xiao-Ping
Su, Ming
Hu, Xu
Sun, Zheng
Li, Gang
Li, Li-Ming
Mu, Li-Na
Lu, Qing-Yi
Zhao, Jin-Kou
Zhang, Zuo-Feng
author_facet Zhu, Yu-Hui
Jeong, Somee
Wu, Ming
Jin, Zi-Yi
Zhou, Jin-Yi
Han, Ren-Qiang
Yang, Jie
Zhang, Xiao-Feng
Wang, Xu-Shan
Liu, Ai-Ming
Gu, Xiao-Ping
Su, Ming
Hu, Xu
Sun, Zheng
Li, Gang
Li, Li-Ming
Mu, Li-Na
Lu, Qing-Yi
Zhao, Jin-Kou
Zhang, Zuo-Feng
author_sort Zhu, Yu-Hui
collection PubMed
description To investigate the associations between dietary fatty acids and cholesterol consumption and stomach cancer (SC), we analyzed data from a population-based case-control study with a total of 1900 SC cases and 6532 controls. Dietary data and other risk or protective factors were collected by face-to-face interviews in Jiangsu Province, China, from 2003 to 2010. Adjusted odds ratios (ORs) and 95% confidence intervals (CIs) were estimated using multiple unconditional logistic regression models and an energy-adjusted method. The joint associations between dietary factors and known risk factors on SC were examined. We observed positive associations between dietary saturated fatty acids (SFAs), monounsaturated fatty acids (MUFAs), and total cholesterol and the development of SC, comparing the highest versus lowest quarters. Increased intakes of dietary SFAs (p-trend = 0.005; aOR, 1.11; 95% CI, 1.01–1.22 with a 7 g/day increase as a continuous variable) and total cholesterol (p-trend < 0.001; aOR, 1.13; 95% CI, 1.06–1.22 with a 250 mg/day increase as a continuous variable) were monotonically associated with elevated odds of developing SC. Our results indicate that dietary SFAs, MUFAs, and total cholesterol are associated with stomach cancer, which might provide a potential dietary intervention for stomach cancer prevention.
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spelling pubmed-67236372019-09-10 Dietary Intake of Fatty Acids, Total Cholesterol, and Stomach Cancer in a Chinese Population Zhu, Yu-Hui Jeong, Somee Wu, Ming Jin, Zi-Yi Zhou, Jin-Yi Han, Ren-Qiang Yang, Jie Zhang, Xiao-Feng Wang, Xu-Shan Liu, Ai-Ming Gu, Xiao-Ping Su, Ming Hu, Xu Sun, Zheng Li, Gang Li, Li-Ming Mu, Li-Na Lu, Qing-Yi Zhao, Jin-Kou Zhang, Zuo-Feng Nutrients Article To investigate the associations between dietary fatty acids and cholesterol consumption and stomach cancer (SC), we analyzed data from a population-based case-control study with a total of 1900 SC cases and 6532 controls. Dietary data and other risk or protective factors were collected by face-to-face interviews in Jiangsu Province, China, from 2003 to 2010. Adjusted odds ratios (ORs) and 95% confidence intervals (CIs) were estimated using multiple unconditional logistic regression models and an energy-adjusted method. The joint associations between dietary factors and known risk factors on SC were examined. We observed positive associations between dietary saturated fatty acids (SFAs), monounsaturated fatty acids (MUFAs), and total cholesterol and the development of SC, comparing the highest versus lowest quarters. Increased intakes of dietary SFAs (p-trend = 0.005; aOR, 1.11; 95% CI, 1.01–1.22 with a 7 g/day increase as a continuous variable) and total cholesterol (p-trend < 0.001; aOR, 1.13; 95% CI, 1.06–1.22 with a 250 mg/day increase as a continuous variable) were monotonically associated with elevated odds of developing SC. Our results indicate that dietary SFAs, MUFAs, and total cholesterol are associated with stomach cancer, which might provide a potential dietary intervention for stomach cancer prevention. MDPI 2019-07-26 /pmc/articles/PMC6723637/ /pubmed/31357492 http://dx.doi.org/10.3390/nu11081730 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Zhu, Yu-Hui
Jeong, Somee
Wu, Ming
Jin, Zi-Yi
Zhou, Jin-Yi
Han, Ren-Qiang
Yang, Jie
Zhang, Xiao-Feng
Wang, Xu-Shan
Liu, Ai-Ming
Gu, Xiao-Ping
Su, Ming
Hu, Xu
Sun, Zheng
Li, Gang
Li, Li-Ming
Mu, Li-Na
Lu, Qing-Yi
Zhao, Jin-Kou
Zhang, Zuo-Feng
Dietary Intake of Fatty Acids, Total Cholesterol, and Stomach Cancer in a Chinese Population
title Dietary Intake of Fatty Acids, Total Cholesterol, and Stomach Cancer in a Chinese Population
title_full Dietary Intake of Fatty Acids, Total Cholesterol, and Stomach Cancer in a Chinese Population
title_fullStr Dietary Intake of Fatty Acids, Total Cholesterol, and Stomach Cancer in a Chinese Population
title_full_unstemmed Dietary Intake of Fatty Acids, Total Cholesterol, and Stomach Cancer in a Chinese Population
title_short Dietary Intake of Fatty Acids, Total Cholesterol, and Stomach Cancer in a Chinese Population
title_sort dietary intake of fatty acids, total cholesterol, and stomach cancer in a chinese population
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723637/
https://www.ncbi.nlm.nih.gov/pubmed/31357492
http://dx.doi.org/10.3390/nu11081730
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