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Systemic Sclerosis Serum Steers the Differentiation of Adipose-Derived Stem Cells Toward Profibrotic Myofibroblasts: Pathophysiologic Implications
Systemic sclerosis (SSc; scleroderma) is characterized by life-threatening progressive multiorgan fibrosis orchestrated by profibrotic myofibroblasts originating from different sources. Because recent data demonstrated that the majority of myofibroblasts in a murine scleroderma model arise from adip...
Autores principales: | Manetti, Mirko, Romano, Eloisa, Rosa, Irene, Fioretto, Bianca Saveria, Praino, Emanuela, Guiducci, Serena, Iannone, Florenzo, Ibba-Manneschi, Lidia, Matucci-Cerinic, Marco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723717/ https://www.ncbi.nlm.nih.gov/pubmed/31430950 http://dx.doi.org/10.3390/jcm8081256 |
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