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Effects of Chain Length of Chitosan Oligosaccharides on Solution Properties and Complexation with siRNA

In the context of gene delivery, chitosan has been widely used as a safe and effective polycation to complex DNA, RNA and more recently, siRNA. However, much less attention has been paid to chitosan oligosaccharides (COS) despite their biological properties. This study proposed to carry out a physic...

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Detalles Bibliográficos
Autores principales: Delas, Tim, Mock-Joubert, Maxime, Faivre, Jimmy, Hofmaier, Mirjam, Sandre, Olivier, Dole, François, Chapel, Jean Paul, Crépet, Agnès, Trombotto, Stéphane, Delair, Thierry, Schatz, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723797/
https://www.ncbi.nlm.nih.gov/pubmed/31349712
http://dx.doi.org/10.3390/polym11081236