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In-Depth Bioinformatic Study of the CLDN16 Gene and Protein: Prediction of Subcellular Localization to Mitochondria
Background and Objectives: The defects in the CLDN16 gene are a cause of primary hypomagnesemia (FHHNC), which is characterized by massive renal magnesium wasting, resulting in nephrocalcinosis and renal failure. The mutations occur throughout the gene’s coding region and can impact on intracellular...
Autores principales: | Rouka, Erasmia, Liakopoulos, Vassilios, Gourgoulianis, Konstantinos I., Hatzoglou, Chrissi, Zarogiannis, Sotirios G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723856/ https://www.ncbi.nlm.nih.gov/pubmed/31357502 http://dx.doi.org/10.3390/medicina55080409 |
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