Indoxyl Sulfate Stimulates Angiogenesis by Regulating Reactive Oxygen Species Production via CYP1B1

Indoxyl sulfate (IS) is an accumulative protein-bound uremic toxin found in patients with kidney disease. It is reported that IS impairs the vascular endothelium, but a comprehensive overview of all mechanisms active in IS-injury currently remains lacking. Here we performed RNA sequencing in human u...

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Detalles Bibliográficos
Autores principales: Pei, Jiayi, Juni, Rio, Harakalova, Magdalena, Duncker, Dirk J., Asselbergs, Folkert W., Koolwijk, Pieter, van Hinsbergh, Victor, Verhaar, Marianne C., Mokry, Michal, Cheng, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723868/
https://www.ncbi.nlm.nih.gov/pubmed/31382511
http://dx.doi.org/10.3390/toxins11080454

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