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Vaccine Adjuvants Derived from Marine Organisms

Vaccine adjuvants help to enhance the immunogenicity of weak antigens. The adjuvant effect of certain substances was noted long ago (the 40s of the last century), and since then a large number of adjuvants belonging to different groups of chemicals have been studied. This review presents research da...

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Detalles Bibliográficos
Autor principal: Sanina, Nina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723903/
https://www.ncbi.nlm.nih.gov/pubmed/31382606
http://dx.doi.org/10.3390/biom9080340
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author Sanina, Nina
author_facet Sanina, Nina
author_sort Sanina, Nina
collection PubMed
description Vaccine adjuvants help to enhance the immunogenicity of weak antigens. The adjuvant effect of certain substances was noted long ago (the 40s of the last century), and since then a large number of adjuvants belonging to different groups of chemicals have been studied. This review presents research data on the nonspecific action of substances originated from marine organisms, their derivatives and complexes, united by the name ‘adjuvants’. There are covered the mechanisms of their action, safety, as well as the practical use of adjuvants derived from marine hydrobionts in medical immunology and veterinary medicine to create modern vaccines that should be non-toxic and efficient. The present review is intended to briefly describe some important achievements in the use of marine resources to solve this important problem.
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spelling pubmed-67239032019-09-10 Vaccine Adjuvants Derived from Marine Organisms Sanina, Nina Biomolecules Review Vaccine adjuvants help to enhance the immunogenicity of weak antigens. The adjuvant effect of certain substances was noted long ago (the 40s of the last century), and since then a large number of adjuvants belonging to different groups of chemicals have been studied. This review presents research data on the nonspecific action of substances originated from marine organisms, their derivatives and complexes, united by the name ‘adjuvants’. There are covered the mechanisms of their action, safety, as well as the practical use of adjuvants derived from marine hydrobionts in medical immunology and veterinary medicine to create modern vaccines that should be non-toxic and efficient. The present review is intended to briefly describe some important achievements in the use of marine resources to solve this important problem. MDPI 2019-08-03 /pmc/articles/PMC6723903/ /pubmed/31382606 http://dx.doi.org/10.3390/biom9080340 Text en © 2019 by the author. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Sanina, Nina
Vaccine Adjuvants Derived from Marine Organisms
title Vaccine Adjuvants Derived from Marine Organisms
title_full Vaccine Adjuvants Derived from Marine Organisms
title_fullStr Vaccine Adjuvants Derived from Marine Organisms
title_full_unstemmed Vaccine Adjuvants Derived from Marine Organisms
title_short Vaccine Adjuvants Derived from Marine Organisms
title_sort vaccine adjuvants derived from marine organisms
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6723903/
https://www.ncbi.nlm.nih.gov/pubmed/31382606
http://dx.doi.org/10.3390/biom9080340
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