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Correlation analysis of metabolic syndrome and its components with thyroid nodules
OBJECTIVE: This study aimed to analyze the relationship between the metabolic syndrome (MetS) and its components with the occurrence of thyroid nodules. METHODS: A total of 2719 volunteers from some areas of Gansu Province, China, who participated in the national survey of thyroid diseases and iodin...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724178/ https://www.ncbi.nlm.nih.gov/pubmed/31564932 http://dx.doi.org/10.2147/DMSO.S219019 |
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author | Liu, Jingfang Wang, Chenge Tang, Xulei Fu, Songbo Jing, Gaojing Ma, Lihua Sun, Weiming Li, Yujuan Wu, Dan Niu, Ying Niu, Qianglong Guo, Huiping Song, Pei |
author_facet | Liu, Jingfang Wang, Chenge Tang, Xulei Fu, Songbo Jing, Gaojing Ma, Lihua Sun, Weiming Li, Yujuan Wu, Dan Niu, Ying Niu, Qianglong Guo, Huiping Song, Pei |
author_sort | Liu, Jingfang |
collection | PubMed |
description | OBJECTIVE: This study aimed to analyze the relationship between the metabolic syndrome (MetS) and its components with the occurrence of thyroid nodules. METHODS: A total of 2719 volunteers from some areas of Gansu Province, China, who participated in the national survey of thyroid diseases and iodine nutrition status (Tide) and diabetes prevalence, were selected. Their height, weight, waist circumference (WC), systolic blood pressure (SBP), and diastolic blood pressure were recorded. The fasting plasma glucose (FPG), 2-h plasma postprandial glucose (2hPG), total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and glycosylated hemoglobin (HbA1C) levels were measured. The prevalence of MetS and thyroid nodules was evaluated, and the correlation between each component of MetS and thyroid nodules was studied. RESULTS: The prevalence of MetS and thyroid nodules was 15.4% and 17.2%, respectively. WC, SBP, body mass index, FPG, 2hPG, TG, TC, and thyroid-stimulating hormone levels were significantly higher in the thyroid nodule group. The prevalence of thyroid nodules was significantly higher in the MetS group. A positive correlation was found between the degree of metabolic disorder and the occurrence of thyroid nodules. WC was found to be a risk factor for the occurrence of thyroid nodules. For WC≥90 cm, an increase in the independent variables led to a significant rise in the incidence of thyroid nodules. CONCLUSION: The prevalence of thyroid nodules was higher in the MetS group. The WC of the MetS components might be an independent risk factor for the occurrence of thyroid nodules. |
format | Online Article Text |
id | pubmed-6724178 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-67241782019-09-27 Correlation analysis of metabolic syndrome and its components with thyroid nodules Liu, Jingfang Wang, Chenge Tang, Xulei Fu, Songbo Jing, Gaojing Ma, Lihua Sun, Weiming Li, Yujuan Wu, Dan Niu, Ying Niu, Qianglong Guo, Huiping Song, Pei Diabetes Metab Syndr Obes Original Research OBJECTIVE: This study aimed to analyze the relationship between the metabolic syndrome (MetS) and its components with the occurrence of thyroid nodules. METHODS: A total of 2719 volunteers from some areas of Gansu Province, China, who participated in the national survey of thyroid diseases and iodine nutrition status (Tide) and diabetes prevalence, were selected. Their height, weight, waist circumference (WC), systolic blood pressure (SBP), and diastolic blood pressure were recorded. The fasting plasma glucose (FPG), 2-h plasma postprandial glucose (2hPG), total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and glycosylated hemoglobin (HbA1C) levels were measured. The prevalence of MetS and thyroid nodules was evaluated, and the correlation between each component of MetS and thyroid nodules was studied. RESULTS: The prevalence of MetS and thyroid nodules was 15.4% and 17.2%, respectively. WC, SBP, body mass index, FPG, 2hPG, TG, TC, and thyroid-stimulating hormone levels were significantly higher in the thyroid nodule group. The prevalence of thyroid nodules was significantly higher in the MetS group. A positive correlation was found between the degree of metabolic disorder and the occurrence of thyroid nodules. WC was found to be a risk factor for the occurrence of thyroid nodules. For WC≥90 cm, an increase in the independent variables led to a significant rise in the incidence of thyroid nodules. CONCLUSION: The prevalence of thyroid nodules was higher in the MetS group. The WC of the MetS components might be an independent risk factor for the occurrence of thyroid nodules. Dove 2019-08-30 /pmc/articles/PMC6724178/ /pubmed/31564932 http://dx.doi.org/10.2147/DMSO.S219019 Text en © 2019 Liu et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Original Research Liu, Jingfang Wang, Chenge Tang, Xulei Fu, Songbo Jing, Gaojing Ma, Lihua Sun, Weiming Li, Yujuan Wu, Dan Niu, Ying Niu, Qianglong Guo, Huiping Song, Pei Correlation analysis of metabolic syndrome and its components with thyroid nodules |
title | Correlation analysis of metabolic syndrome and its components with thyroid nodules |
title_full | Correlation analysis of metabolic syndrome and its components with thyroid nodules |
title_fullStr | Correlation analysis of metabolic syndrome and its components with thyroid nodules |
title_full_unstemmed | Correlation analysis of metabolic syndrome and its components with thyroid nodules |
title_short | Correlation analysis of metabolic syndrome and its components with thyroid nodules |
title_sort | correlation analysis of metabolic syndrome and its components with thyroid nodules |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724178/ https://www.ncbi.nlm.nih.gov/pubmed/31564932 http://dx.doi.org/10.2147/DMSO.S219019 |
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