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NPA: an R package for computing network perturbation amplitudes using gene expression data and two-layer networks
BACKGROUND: High-throughput gene expression technologies provide complex datasets reflecting mechanisms perturbed in an experiment, typically in a treatment versus control design. Analysis of these information-rich data can be guided based on a priori knowledge, such as networks of related proteins...
Autores principales: | Martin, Florian, Gubian, Sylvain, Talikka, Marja, Hoeng, Julia, Peitsch, Manuel C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724309/ https://www.ncbi.nlm.nih.gov/pubmed/31481014 http://dx.doi.org/10.1186/s12859-019-3016-x |
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