Cargando…

Associations between biomarkers of bone and cartilage turnover, gender, pain categories and radiographic severity in knee osteoarthritis

BACKGROUND: Excessive cartilage degradation is a known characteristic of osteoarthritis (OA). Biochemical markers, such as uCTX-II, have been shown to be associated with disease severity, yet the tissue origin of CTX-II has been disputed. This analysis investigates the association between OA knee jo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bihlet, Asger Reinstrup, Byrjalsen, Inger, Bay-Jensen, Anne-Christine, Andersen, Jeppe Ragnar, Christiansen, Claus, Riis, Bente Juel, Karsdal, Morten A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724319/ https://www.ncbi.nlm.nih.gov/pubmed/31481084 http://dx.doi.org/10.1186/s13075-019-1987-7

Ejemplares similares

The Efficacy and Safety of Multiple Dose Regimens of Kudzu (Pueraria lobata) Root Extract on Bone and Cartilage Turnover and Menopausal Symptoms
por: Bihlet, Asger Reinstrup, et al.
Publicado: (2021)

Identification of pain categories associated with change in pain in patients receiving placebo: data from two phase 3 randomized clinical trials in symptomatic knee osteoarthritis
por: Bihlet, Asger Reinstrup, et al.
Publicado: (2018)

Serum C-reactive protein metabolite (CRPM) is associated with incidence of contralateral knee osteoarthritis
por: Bay-Jensen, Anne-Christine, et al.
Publicado: (2021)

Evaluation of serum ARGS neoepitope as an osteoarthritis biomarker using a standardized model for exercise-induced cartilage extra cellular matrix turnover
por: Bjerre-Bastos, Jonathan J., et al.
Publicado: (2020)

Optimizing bioavailability of oral administration of small peptides through pharmacokinetic and pharmacodynamic parameters: The effect of water and timing of meal intake on oral delivery of Salmon Calcitonin
por: Karsdal, Morten A, et al.
Publicado: (2008)

Matrix Metalloproteinase Mediated Type I Collagen Degradation is an Independent Predictor of Increased Risk of Acute Myocardial Infarction in Postmenopausal Women
por: Bertelsen, Ditte Marie, et al.
Publicado: (2018)

Incidence of total hip and total knee replacements from the prospective epidemiologic risk factor study: considerations for event driven clinical trial design
por: Bager, Cecilie L., et al.
Publicado: (2019)

Biomarkers of extracellular matrix turnover are associated with emphysema and eosinophilic-bronchitis in COPD
por: Bihlet, Asger Reinstrup, et al.
Publicado: (2017)

Serological Biomarkers of Joint Tissue Turnover Predict Tocilizumab Response at Baseline
por: Bay-Jensen, Anne C., et al.
Publicado: (2014)

Long-term structural and symptomatic effects of intra-articular sprifermin in patients with knee osteoarthritis: 5-year results from the FORWARD study
por: Eckstein, Felix, et al.
Publicado: (2021)

A low cartilage formation and repair endotype predicts radiographic progression of symptomatic knee osteoarthritis
por: Luo, Yunyun, et al.
Publicado: (2021)

Biomarkers of collagen turnover are related to annual change in FEV(1) in patients with chronic obstructive pulmonary disease within the ECLIPSE study
por: Leeming, Diana J., et al.
Publicado: (2017)

Biochemical markers identify influences on bone and cartilage degradation in osteoarthritis - the effect of sex, Kellgren-Lawrence (KL) score, Body Mass Index (BMI), oral salmon calcitonin (sCT) treatment and diurnal variation
por: Karsdal, MA, et al.
Publicado: (2010)

Circulating Protein Fragments of Cartilage and Connective Tissue Degradation Are Diagnostic and Prognostic Markers of Rheumatoid Arthritis and Ankylosing Spondylitis
por: Bay-Jensen, Anne C., et al.
Publicado: (2013)

Associations between single-question Visual Analogue Scale pain score and weight-bearing and non–weight-bearing domains of Western Ontario and McMaster Universities Arthritis Index pain: data from 2 phase 3 clinical trials
por: Bjerre-Bastos, Jonathan J., et al.
Publicado: (2022)

Early changes in blood-based joint tissue destruction biomarkers are predictive of response to tocilizumab in the LITHE study
por: Bay-Jensen, Anne C., et al.
Publicado: (2016)

Does increased local bone resorption secondary to breast and prostate cancer result in increased cartilage degradation?
por: Leeming, Diana J, et al.
Publicado: (2008)

High levels of biomarkers of collagen remodeling are associated with increased mortality in COPD – results from the ECLIPSE study
por: Sand, Jannie M. B., et al.
Publicado: (2016)

Tibolone inhibits bone resorption without secondary positive effects on cartilage degradation
por: Karsdal, MA, et al.
Publicado: (2008)

Investigation of the diurnal variation in bone resorption for optimal drug delivery and efficacy in osteoporosis with oral calcitonin
por: Karsdal, MA, et al.
Publicado: (2008)

The active form of MMP-3 is a marker of synovial inflammation and cartilage turnover in inflammatory joint diseases
por: Sun, Shu, et al.
Publicado: (2014)

Cartilage Turnover Reflected by Metabolic Processing of Type II Collagen: A Novel Marker of Anabolic Function in Chondrocytes
por: Gudmann, Natasja Stæhr, et al.
Publicado: (2014)

Collagen Type III and VI Turnover in Response to Long-Term Immobilization
por: Sun, Shu, et al.
Publicado: (2015)

Matrix Metalloproteinase-dependent turnover of cartilage, synovial membrane, and connective tissue is elevated in rats with collagen induced arthritis
por: Siebuhr, Anne Sofie, et al.
Publicado: (2012)

Characterization of an Ex vivo Femoral Head Model Assessed by Markers of Bone and Cartilage Turnover
por: Madsen, Suzi Hoegh, et al.
Publicado: (2011)

Serological identification of fast progressors of structural damage with rheumatoid arthritis
por: Siebuhr, Anne Sofie, et al.
Publicado: (2013)

Human macrophage foam cells degrade atherosclerotic plaques through cathepsin K mediated processes
por: Barascuk, Natasha, et al.
Publicado: (2010)

Identification of progressors in osteoarthritis by combining biochemical and MRI-based markers
por: Dam, Erik B, et al.
Publicado: (2009)

Sprifermin (rhFGF18) modulates extracellular matrix turnover in cartilage explants ex vivo
por: Reker, Ditte, et al.
Publicado: (2017)

Serum cartilage oligomeric matrix protein and development of radiographic and painful knee osteoarthritis. A community-based cohort of middle-aged women
por: Kluzek, Stefan, et al.
Publicado: (2015)

Diagnosis of Osteoarthritis by Cartilage Surface Smoothness Quantified Automatically from Knee MRI
por: Tummala, Sudhakar, et al.
Publicado: (2011)

The Effect of Protease Inhibitors on the Induction of Osteoarthritis-Related Biomarkers in Bovine Full-Depth Cartilage Explants
por: He, Yi, et al.
Publicado: (2015)

PLCL1 rs7595412 variation is not associated with hip bone size variation in postmenopausal Danish women
por: Cauchi, Stéphane, et al.
Publicado: (2009)

Blood and urine biomarkers in osteoarthritis – an update on cartilage associated type II collagen and aggrecan markers
por: Bay-Jensen, Anne C., et al.
Publicado: (2022)

Cartilage degradation is fully reversible in the presence of aggrecanase but not matrix metalloproteinase activity
por: Karsdal, Morten A, et al.
Publicado: (2008)

The minor collagens in articular cartilage
por: Luo, Yunyun, et al.
Publicado: (2017)

Bone and Cartilage Turnover Markers, Bone Mineral Density, and Radiographic Damage in Men with Ankylosing Spondylitis
por: Park, Min-Chan, et al.
Publicado: (2008)

Association between Markers of Synovial Inflammation, Matrix Turnover and Symptoms in Knee Osteoarthritis: A Cross-Sectional Study
por: Yang, Xiaotian, et al.
Publicado: (2021)

Tissue metabolite of type I collagen, C1M, and CRP predicts structural progression of rheumatoid arthritis
por: Bay-Jensen, Anne C., et al.
Publicado: (2019)

Effect of n-3 PUFA on extracellular matrix protein turnover in patients with psoriatic arthritis: a randomized, double-blind, placebo-controlled trial
por: Holm Nielsen, Signe, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_tndg73llg33tg64rc0bfrvgars