Notch Signaling Inhibition by LY411575 Attenuates Osteoblast Differentiation and Decreased Ectopic Bone Formation Capacity of Human Skeletal (Mesenchymal) Stem Cells

BACKGROUND: Chemical biology approaches using small molecule inhibitors targeting specific signaling pathways are useful tools to dissect the molecular mechanisms governing stem cell differentiation and for their possible use in therapeutic interventions. METHODS: Stem cell signaling small molecule...

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Detalles Bibliográficos
Autores principales: AlMuraikhi, Nihal, Ali, Dalia, Vishnubalaji, Radhakrishnan, Manikandan, Muthurangan, Atteya, Muhammad, Siyal, Abdulaziz, Alfayez, Musaad, Aldahmash, Abdullah, Kassem, Moustapha, Alajez, Nehad M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724428/
https://www.ncbi.nlm.nih.gov/pubmed/31534459
http://dx.doi.org/10.1155/2019/3041262

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