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Regulation of LC3 lipidation by the autophagy-specific class III phosphatidylinositol-3 kinase complex
Autophagy is a conserved eukaryotic pathway critical for cellular adaptation to changes in nutrition levels and stress. The class III phosphatidylinositol (PI)3-kinase complexes I and II (PI3KC3-C1 and -C2) are essential for autophagosome initiation and maturation, respectively, from highly curved v...
Autores principales: | Brier, Livia W., Ge, Liang, Stjepanovic, Goran, Thelen, Ashley M., Hurley, James H., Schekman, Randy |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724508/ https://www.ncbi.nlm.nih.gov/pubmed/30811270 http://dx.doi.org/10.1091/mbc.E18-11-0743 |
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