Retromer facilitates the localization of Bcl-xL to the mitochondrial outer membrane

The anti-apoptotic Bcl-2 family protein Bcl-xL plays a critical role in cell survival by protecting the integrity of the mitochondrial outer membrane (MOM). The mechanism through which Bcl-xL is recruited to the MOM has not been fully discerned. The retromer is a conserved endosomal scaffold complex...

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Detalles Bibliográficos
Autores principales: Farmer, Trey, O’Neill, Katelyn L., Naslavsky, Naava, Luo, Xu, Caplan, Steve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2019
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724524/
https://www.ncbi.nlm.nih.gov/pubmed/30840537
http://dx.doi.org/10.1091/mbc.E19-01-0044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724524/
https://www.ncbi.nlm.nih.gov/pubmed/30840537
http://dx.doi.org/10.1091/mbc.E19-01-0044

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