Myosin II governs intracellular pressure and traction by distinct tropomyosin-dependent mechanisms

Two-dimensional (2D) substrate rigidity promotes myosin II activity to increase traction force in a process negatively regulated by tropomyosin (Tpm) 2.1. We recently discovered that actomyosin contractility can increase intracellular pressure and switch tumor cells from low-pressure lamellipodia to...

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Detalles Bibliográficos
Autores principales: Sao, Kimheak, Jones, Tia M., Doyle, Andrew D., Maity, Debonil, Schevzov, Galina, Chen, Yun, Gunning, Peter W., Petrie, Ryan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724525/
https://www.ncbi.nlm.nih.gov/pubmed/30865560
http://dx.doi.org/10.1091/mbc.E18-06-0355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724525/
https://www.ncbi.nlm.nih.gov/pubmed/30865560
http://dx.doi.org/10.1091/mbc.E18-06-0355

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