Cargando…

Gami–Chunggan Formula Prevents Motor Dysfunction in MPTP/p-Induced and A53T α-Synuclein Overexpressed Parkinson’s Disease Mouse Model Though DJ-1 and BDNF Expression

The Gami–Chunggan formula (GCF) is a modification of the Chunggan (CG) decoction, which has been used to treat movement disorders such as Parkinson’s disease (PD) in Traditional East Asian Medicine. To evaluate the neuroprotective effects of GCF in chronic PD animal models, we used either a 5-week t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ahn, Sora, Liu, Quan Feng, Jang, Jae-Hwan, Park, Jeonghun, Jeong, Ha Jin, Kim, Youngman, Kim, Dong-hee, Jeong, Guwon, Oh, Seung Tack, Park, Seong-Uk, Cho, Seung-Yeon, Park, Hi-Joon, Jeon, Songhee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724569/ https://www.ncbi.nlm.nih.gov/pubmed/31555122 http://dx.doi.org/10.3389/fnagi.2019.00230

Ejemplares similares

MPTP-induced vulnerability of dopamine neurons in A53T α-synuclein overexpressed mice with the potential involvement of DJ-1 downregulation
por: Lee, Seongmi, et al.
Publicado: (2017)

Effects of Combined Treatment with Acupuncture and Chunggan Formula in a Mouse Model of Parkinson's Disease
por: Hwang, Tae-Yeon, et al.
Publicado: (2019)

The effects of Sutaehwan-Gami on menopausal symptoms induced by ovariectomy in rats
por: Kim, Dong-Il, et al.
Publicado: (2012)

A Comprehensive Phenotype of Non-motor Impairments and Distribution of Alpha-Synuclein Deposition in Parkinsonism-Induced Mice by a Combination Injection of MPTP and Probenecid
por: Han, Na-Ra, et al.
Publicado: (2021)

α-Synuclein accumulation and GBA deficiency due to L444P GBA mutation contributes to MPTP-induced parkinsonism
por: Yun, Seung Pil, et al.
Publicado: (2018)

Pharmacological Effects of Gami-Yukmijihwang-Tang on the Lipopolysaccharide-Induced Hippocampus Oxidation and Inflammation via Regulation of Sirt6
por: Kang, Jie-Yoon, et al.
Publicado: (2022)

The (Gami)fictional Ego-Center: Projecting the Location of the Self Into an Avatar
por: Friehs, Maximilian A., et al.
Publicado: (2022)

Modulation of experimental atopic dermatitis by topical application of Gami-Cheongyeul-Sodok-Eum
por: Hwang, Ji Sun, et al.
Publicado: (2013)

Neuroprotective Effects of Gagam-Sipjeondaebo-Tang, a Novel Herbal Formula, against MPTP-Induced Parkinsonian Mice and MPP(+)-Induced Cell Death in SH-SY5Y Cells
por: Ko, Jade Heejae, et al.
Publicado: (2018)

Exercise Does Not Protect against MPTP-Induced Neurotoxicity in BDNF Happloinsufficent Mice
por: Gerecke, Kim M., et al.
Publicado: (2012)

Analysis and Identification of Active Compounds from Gami-Soyosan Toxic to MCF-7 Human Breast Adenocarcinoma Cells
por: Jung, Mi-Yeon, et al.
Publicado: (2019)

Necrosulfonamide exerts neuroprotective effect by inhibiting necroptosis, neuroinflammation, and α-synuclein oligomerization in a subacute MPTP mouse model of Parkinson’s disease
por: Leem, Yea-Hyun, et al.
Publicado: (2023)

DJ-1 Acts as a Scavenger of α-Synuclein Oligomers and Restores Monomeric Glycated α-Synuclein
por: Atieh, Tamr B., et al.
Publicado: (2021)

BiGAMi: Bi-Objective Genetic Algorithm Fitness Function for Feature Selection on Microbiome Datasets
por: Leske, Mike, et al.
Publicado: (2022)

Herbal medicine (Hepad) prevents dopaminergic neuronal death in the rat MPTP model of Parkinson’s disease
por: Kim, Dong Hee, et al.
Publicado: (2019)

DJ-1 controls bone homeostasis through the regulation of osteoclast differentiation
por: Kim, Hyuk Soon, et al.
Publicado: (2017)

Partially oxidized DJ-1 inhibits α-synuclein nucleation and remodels mature α-synuclein fibrils in vitro
por: Kumar, Roshan, et al.
Publicado: (2019)

α-Synuclein and DJ-1 as Potential Biological Fluid Biomarkers for Parkinson’s Disease
por: Waragai, Masaaki, et al.
Publicado: (2010)

DJ-1 Inhibits α-Synuclein Aggregation by Regulating Chaperone-Mediated Autophagy
por: Xu, Chuan-Ying, et al.
Publicado: (2017)

Resistance to MPTP-Neurotoxicity in α-Synuclein Knockout Mice Is Complemented by Human α-Synuclein and Associated with Increased β-Synuclein and Akt Activation
por: Thomas, Bobby, et al.
Publicado: (2011)

Interested, Though Not Competing
por: Snell, A. Saxon
Publicado: (1912)

DJ-1 Null Dopaminergic Neuronal Cells Exhibit Defects in Mitochondrial Function and Structure: Involvement of Mitochondrial Complex I Assembly
por: Heo, Jun Young, et al.
Publicado: (2012)

The Resveratrol Rice DJ526 Callus Significantly Increases the Lifespan of Drosophila (Resveratrol Rice DJ526 Callus for Longevity)
por: Khan, Mousumee, et al.
Publicado: (2019)

Correction: Resistance to MPTP-Neurotoxicity in α-Synuclein Knockout Mice Is Complemented by Human α-Synuclein and Associated with Increased β-Synuclein and Akt Activation
por: Thomas, Bobby, et al.
Publicado: (2012)

Batryticatus Bombyx Protects Dopaminergic Neurons against MPTP-Induced Neurotoxicity by Inhibiting Oxidative Damage
por: Lim, Hye-Sun, et al.
Publicado: (2019)

A combined physical–chemical and microbiological approach to unveil the fabrication, provenance, and state of conservation of the Kinkarakawa-gami art
por: Piacenza, Elena, et al.
Publicado: (2020)

DeepGAMI: deep biologically guided auxiliary learning for multimodal integration and imputation to improve genotype–phenotype prediction
por: Chandrashekar, Pramod Bharadwaj, et al.
Publicado: (2023)

How to Be Happy Though Human
Publicado: (1957)

An Unpleasant Though Interesting Experience
por: Brown, Jno. E.
Publicado: (1896)

Phosphorylation of Tau and α-Synuclein Induced Neurodegeneration in MPTP Mouse Model of Parkinson’s Disease
por: Hu, Shanshan, et al.
Publicado: (2020)

Synuclein Proteins in MPTP-Induced Death of Substantia Nigra Pars Compacta Dopaminergic Neurons
por: Goloborshcheva, Valeria V., et al.
Publicado: (2022)

Association between Decreased SGK1 and Increased Intestinal α-Synuclein in an MPTP Mouse Model of Parkinson’s Disease
por: Seo, Min Hyung, et al.
Publicado: (2023)

Regulation of BDNF transcription by Nrf2 and MeCP2 ameliorates MPTP-induced neurotoxicity
por: Cao, Qianqian, et al.
Publicado: (2022)

Association between BDNF Gene Polymorphisms and Serotonergic Activity Using Loudness Dependence of Auditory Evoked Potentials in Healthy Subjects
por: Park, Young-Min, et al.
Publicado: (2013)

DJ-1 Is a Redox-Dependent Molecular Chaperone That Inhibits α-Synuclein Aggregate Formation
por: Shendelman, Shoshana, et al.
Publicado: (2004)

DJ-1 interactions with α-synuclein attenuate aggregation and cellular toxicity in models of Parkinson's disease
por: Zondler, L, et al.
Publicado: (2014)

β-synuclein potentiates synaptic vesicle dopamine uptake and rescues dopaminergic neurons from MPTP-induced death in the absence of other synucleins
por: Ninkina, Natalia, et al.
Publicado: (2021)

Novel analgesic effects of melanin-concentrating hormone on persistent neuropathic and inflammatory pain in mice
por: Jang, Jae-Hwan, et al.
Publicado: (2018)

Drosophila DJ-1 Decreases Neural Sensitivity to Stress by Negatively Regulating Daxx-Like Protein through dFOXO
por: Hwang, Soojin, et al.
Publicado: (2013)

The Effects of Serping1 siRNA in α-Synuclein Regulation in MPTP-Induced Parkinson’s Disease
por: Seo, Min Hyung, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_t1bjd186fjkvmst5uth984lu0p