Cargando…
Hic-5 regulates Src-induced invadopodia rosette formation and organization
Fibroblasts transformed by the proto-oncogene Src form individual invadopodia that can spontaneously self-organize into large matrix-degrading superstructures called rosettes. However, the mechanisms by which the invadopodia can spatiotemporally reorganize their architecture is not well understood....
Autores principales: | Gulvady, Anushree C., Forsythe, Ian J., Turner, Christopher E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724605/ https://www.ncbi.nlm.nih.gov/pubmed/30893012 http://dx.doi.org/10.1091/mbc.E18-10-0629 |
Ejemplares similares
-
The focal adhesion scaffold protein Hic-5 regulates vimentin organization in fibroblasts
por: Vohnoutka, Rishel B., et al.
Publicado: (2019) -
Hic-5 promotes invadopodia formation and invasion during TGF-β–induced epithelial–mesenchymal transition
por: Pignatelli, Jeanine, et al.
Publicado: (2012) -
Hic-5 expression is a major indicator of cancer cell morphology, migration, and plasticity in three-dimensional matrices
por: Gulvady, Anushree C., et al.
Publicado: (2018) -
Hic-5 Regulates Fibrillar Adhesion Formation to Control Tumor Extracellular Matrix Remodeling through Interaction with Tensin1
por: Goreczny, Gregory J., et al.
Publicado: (2018) -
LPP is a Src substrate required for invadopodia formation and efficient breast cancer lung metastasis
por: Ngan, Elaine, et al.
Publicado: (2017)