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Analysis of the roles of phosphatidylinositol-4,5-bisphosphate and individual subunits in assembly, localization, and function of Saccharomyces cerevisiae target of rapamycin complex 2

Eukaryotic cell survival requires maintenance of plasma membrane (PM) homeostasis in response to environmental insults and changes in lipid metabolism. In yeast, a key regulator of PM homeostasis is target of rapamycin (TOR) complex 2 (TORC2), a multiprotein complex containing the evolutionarily con...

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Detalles Bibliográficos
Autores principales: Martinez Marshall, Maria Nieves, Emmerstorfer-Augustin, Anita, Leskoske, Kristin L., Zhang, Lydia H., Li, Biyun, Thorner, Jeremy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724684/
https://www.ncbi.nlm.nih.gov/pubmed/30969890
http://dx.doi.org/10.1091/mbc.E18-10-0682