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An alpha-lipoic acid-decursinol hybrid compound attenuates lipopolysaccharide-mediated inflammation in BV2 and RAW264.7 cells

In this study, the anti-inflammatory effects of α-lipoic acid (LA) and decursinol (Dec) hybrid compound LA-Dec were evaluated and compared with its prodrugs, LA and Dec. LA-Dec dose-dependently inhibited lipopolysaccharide (LPS)-induced nitric oxide (NO) generation in BV2 mouse microglial cells. On...

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Detalles Bibliográficos
Autores principales:	Kwon, Mi-Youn, Park, Jiwon, Kim, Sang-Min, Lee, Jooweon, Cho, Hyeongjin, Park, Jeong-Ho, Han, Inn-Oc
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Biochemistry and Molecular Biology 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726214/ https://www.ncbi.nlm.nih.gov/pubmed/31383251 http://dx.doi.org/10.5483/BMBRep.2019.52.8.144

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