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RBM3 promotes neurogenesis in a niche-dependent manner via IMP2-IGF2 signaling pathway after hypoxic-ischemic brain injury

Hypoxic ischemia (HI) is an acute brain threat across all age groups. Therapeutic hypothermia ameliorates resulting injury in neonates but its side effects prevent routine use in adults. Hypothermia up-regulates a small protein subset that includes RNA-binding motif protein 3 (RBM3), which is neurop...

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Detalles Bibliográficos
Autores principales: Zhu, Xinzhou, Yan, Jingyi, Bregere, Catherine, Zelmer, Andrea, Goerne, Tessa, Kapfhammer, Josef P., Guzman, Raphael, Wellmann, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726629/
https://www.ncbi.nlm.nih.gov/pubmed/31484925
http://dx.doi.org/10.1038/s41467-019-11870-x