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RBM3 promotes neurogenesis in a niche-dependent manner via IMP2-IGF2 signaling pathway after hypoxic-ischemic brain injury
Hypoxic ischemia (HI) is an acute brain threat across all age groups. Therapeutic hypothermia ameliorates resulting injury in neonates but its side effects prevent routine use in adults. Hypothermia up-regulates a small protein subset that includes RNA-binding motif protein 3 (RBM3), which is neurop...
Autores principales: | Zhu, Xinzhou, Yan, Jingyi, Bregere, Catherine, Zelmer, Andrea, Goerne, Tessa, Kapfhammer, Josef P., Guzman, Raphael, Wellmann, Sven |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726629/ https://www.ncbi.nlm.nih.gov/pubmed/31484925 http://dx.doi.org/10.1038/s41467-019-11870-x |
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