The poly-SUMO2/3 protease SENP6 enables assembly of the constitutive centromere-associated network by group deSUMOylation

In contrast to our extensive knowledge on ubiquitin polymer signaling, we are severely limited in our understanding of poly-SUMO signaling. We set out to identify substrates conjugated to SUMO polymers, using knockdown of the poly-SUMO2/3 protease SENP6. We identify over 180 SENP6 regulated proteins...

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Detalles Bibliográficos
Autores principales: Liebelt, Frauke, Jansen, Nicolette S., Kumar, Sumit, Gracheva, Ekaterina, Claessens, Laura A., Verlaan-de Vries, Matty, Willemstein, Edwin, Vertegaal, Alfred C. O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726658/
https://www.ncbi.nlm.nih.gov/pubmed/31485003
http://dx.doi.org/10.1038/s41467-019-11773-x

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