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Prophylactic simvastatin treatment modulates the immune response and increases survival of mice following induction of lethal sepsis
OBJECTIVE: To investigate whether and how simvastatin mediates protection from lethal sepsis, using a mouse model. METHODS: Sixty C57BL/6 mice were selected and divided into three groups (“control,” “model,” and “observation”; n = 20 mice per group). Mice in the model and observation groups underwen...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
SAGE Publications
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726777/ https://www.ncbi.nlm.nih.gov/pubmed/31307265 http://dx.doi.org/10.1177/0300060519858508 |