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Tizanidine hydrochloride exhibits a cytotoxic effect on osteosarcoma cells through the PI3K/AKT signaling pathway

OBJECTIVES: α2-adrenergic receptors are reportedly involved in cancer cell proliferation, invasion, and apoptosis through regulation of diverse molecules, which implies that it contributes to tumor progression. However, the functional significance of α2-adrenergic receptors in osteosarcoma (OS) is u...

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Detalles Bibliográficos
Autores principales: Xing, Xue-Wu, Sun, Yu-Fu, Zhao, Jun, Pan, Zi-Xiang, Jiang, Wen-Xue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726809/
https://www.ncbi.nlm.nih.gov/pubmed/31179788
http://dx.doi.org/10.1177/0300060519850395