Cargando…

Ethanol-Induced Hepatic Insulin Resistance is Ameliorated by Methyl Ferulic Acid Through the PI3K/AKT Signaling Pathway

One of the key events during the development of alcoholic liver disease (ALD) is that alcohol inhibits the insulin signaling pathway in liver and leads to disorders of glucose and lipid metabolism. Methyl ferulic acid (MFA) is a biologically active monomer isolated from the root of Securidaca inappe...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cheng, Qi, Li, Yong Wen, Yang, Cheng Fang, Zhong, Yu Juan, Li, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6726842/ https://www.ncbi.nlm.nih.gov/pubmed/31555134 http://dx.doi.org/10.3389/fphar.2019.00949

Ejemplares similares

Sanghuang Tongxie Formula Ameliorates Insulin Resistance in Drosophila Through Regulating PI3K/Akt Signaling
por: Cao, Xuqing, et al.
Publicado: (2022)

Co-Crystal of Rosiglitazone With Berberine Ameliorates Hyperglycemia and Insulin Resistance Through the PI3K/AKT/TXNIP Pathway In Vivo and In Vitro
por: He, Qichen, et al.
Publicado: (2022)

Ferulic Acid Ameliorates Lipopolysaccharide-Induced Barrier Dysfunction via MicroRNA-200c-3p-Mediated Activation of PI3K/AKT Pathway in Caco-2 Cells
por: He, Shasha, et al.
Publicado: (2020)

Eucommia, Cuscuta, and Drynaria Extracts Ameliorate Glucocorticoid-Induced Osteoporosis by Inhibiting Osteoclastogenesis Through PI3K/Akt Pathway
por: Han, Junwen, et al.
Publicado: (2022)

Tormentic Acid Ameliorates Hepatic Fibrosis in vivo by Inhibiting Glycerophospholipids Metabolism and PI3K/Akt/mTOR and NF-κB Pathways: Based on Transcriptomics and Metabolomics
por: Lin, Xing, et al.
Publicado: (2022)

Rosmarinic Acid Ameliorates Pulmonary Ischemia/Reperfusion Injury by Activating the PI3K/Akt Signaling Pathway
por: Luo, Wenbin, et al.
Publicado: (2022)

Activation of CNR1/PI3K/AKT Pathway by Tanshinone IIA Protects Hippocampal Neurons and Ameliorates Sleep Deprivation-Induced Cognitive Dysfunction in Rats
por: Li, Zi-Heng, et al.
Publicado: (2022)

Ferulic Acid Ameliorates Hepatic Inflammation and Fibrotic Liver Injury by Inhibiting PTP1B Activity and Subsequent Promoting AMPK Phosphorylation
por: Wu, Jianzhi, et al.
Publicado: (2021)

Luteolin Ameliorates Experimental Pulmonary Arterial Hypertension via Suppressing Hippo-YAP/PI3K/AKT Signaling Pathway
por: Zuo, Wanyun, et al.
Publicado: (2021)

Ethanol Extract of Brucea javanica Seed Inhibit Triple-Negative Breast Cancer by Restraining Autophagy via PI3K/Akt/mTOR Pathway
por: Chen, Xiaohong, et al.
Publicado: (2020)

Grape Seed Proanthocyanidin Extract Ameliorates Cardiac Remodelling After Myocardial Infarction Through PI3K/AKT Pathway in Mice
por: Ruan, Yongxue, et al.
Publicado: (2020)

Dec1 Deficiency Ameliorates Pulmonary Fibrosis Through the PI3K/AKT/GSK-3β/β-Catenin Integrated Signaling Pathway
por: Hu, Xingxing, et al.
Publicado: (2022)

Ferulic Acid Ameliorates Atherosclerotic Injury by Modulating Gut Microbiota and Lipid Metabolism
por: Gu, Yuyan, et al.
Publicado: (2021)

Comparing PI3K/Akt Inhibitors Used in Ovarian Cancer Treatment
por: Wu, Yi-Hui, et al.
Publicado: (2020)

Design, synthesis, antiviral activities of ferulic acid derivatives
por: Mao, Jin-long, et al.
Publicado: (2023)

8-Gingerol Ameliorates Myocardial Fibrosis by Attenuating Reactive Oxygen Species, Apoptosis, and Autophagy via the PI3K/Akt/mTOR Signaling Pathway
por: Xue, Yucong, et al.
Publicado: (2021)

Calcium Dobesilate Restores Autophagy by Inhibiting the VEGF/PI3K/AKT/mTOR Signaling Pathway
por: Wang, Yue, et al.
Publicado: (2019)

Incarvillea compacta Maxim ameliorates inflammatory response via inhibiting PI3K/AKT pathway and NLRP3 activation
por: Zhang, Ji, et al.
Publicado: (2022)

Neferine Ameliorates Sepsis-Induced Myocardial Dysfunction Through Anti-Apoptotic and Antioxidative Effects by Regulating the PI3K/AKT/mTOR Signaling Pathway
por: Qi, Zhen, et al.
Publicado: (2021)

Corrigendum: Neferine Ameliorates Sepsis-Induced Myocardial Dysfunction Through Anti-Apoptotic and Antioxidative Effects by Regulating the PI3K/AKT/mTOR Signaling Pathway
por: Qi, Zhen, et al.
Publicado: (2022)

Celastrol Alleviates Autoimmune Hepatitis Through the PI3K/AKT Signaling Pathway Based on Network Pharmacology and Experiments
por: Wang, Shuhui, et al.
Publicado: (2022)

Eldecalcitol prevents muscle loss by suppressing PI3K/AKT/FOXOs pathway in orchiectomized mice
por: Zhang, Haichao, et al.
Publicado: (2022)

Adiponectin Attenuates Lipopolysaccharide-induced Apoptosis by Regulating the Cx43/PI3K/AKT Pathway
por: Liu, Luqian, et al.
Publicado: (2021)

PI3K/AKT Signal Pathway: A Target of Natural Products in the Prevention and Treatment of Alzheimer’s Disease and Parkinson’s Disease
por: Long, Hui-Zhi, et al.
Publicado: (2021)

miR-378b Regulates Insulin Sensitivity by Targeting Insulin Receptor and p110α in Alcohol-Induced Hepatic Steatosis
por: Li, Yuan-yuan, et al.
Publicado: (2020)

Artesunate Combined With Metformin Ameliorate on Diabetes-Induced Xerostomia by Mitigating Superior Salivatory Nucleus and Salivary Glands Injury in Type 2 Diabetic Rats via the PI3K/AKT Pathway
por: Zhang, Siqin, et al.
Publicado: (2021)

Hederagenin Protects PC12 Cells Against Corticosterone-Induced Injury by the Activation of the PI3K/AKT Pathway
por: Lin, Ruohong, et al.
Publicado: (2021)

Azoxystrobin induces apoptosis via PI3K/AKT and MAPK signal pathways in oral leukoplakia progression
por: Li, Lingyu, et al.
Publicado: (2022)

Chuanxiong improves angiogenesis via the PI3K/AKT/Ras/MAPK pathway based on network pharmacology and DESI-MSI metabolomics
por: Cheng, Xue-hao, et al.
Publicado: (2023)

ELA-11 protects the heart against oxidative stress injury induced apoptosis through ERK/MAPK and PI3K/AKT signaling pathways
por: Wang, Xuejun, et al.
Publicado: (2022)

Protective effects and mechanism of puerarin targeting PI3K/Akt signal pathway on neurological diseases
por: Wang, Qian, et al.
Publicado: (2022)

Puerarin inhibited oxidative stress and alleviated cerebral ischemia-reperfusion injury through PI3K/Akt/Nrf2 signaling pathway
por: Zhang, Qianqian, et al.
Publicado: (2023)

Akebia saponin D protects hippocampal neurogenesis from microglia-mediated inflammation and ameliorates depressive-like behaviors and cognitive impairment in mice through the PI3K-Akt pathway
por: Liu, Qin, et al.
Publicado: (2022)

Pretreatment of Huoxue Jiedu Formula Ameliorates Myocardial Ischaemia/Reperfusion Injury by Decreasing Autophagy via Activation of the PI3K/AKT/mTOR Pathway
por: Long, Linzi, et al.
Publicado: (2021)

Terpenoid natural products exert neuroprotection via the PI3K/Akt pathway
por: Xu, Bingyao, et al.
Publicado: (2022)

Progression of the PI3K/Akt signaling pathway in chronic obstructive pulmonary disease
por: Liu, Yanhui, et al.
Publicado: (2023)

Liangxue Jiedu Formula Improves Psoriasis and Dyslipidemia Comorbidity via PI3K/Akt/mTOR Pathway
por: Xie, Xinran, et al.
Publicado: (2021)

Carvacrol Attenuates Diabetic Cardiomyopathy by Modulating the PI3K/AKT/GLUT4 Pathway in Diabetic Mice
por: Hou, Ning, et al.
Publicado: (2019)

Sanhuang Xiexin Tang Ameliorates Type 2 Diabetic Rats via Modulation of the Metabolic Profiles and NF-κB/PI-3K/Akt Signaling Pathways
por: Wei, Xiaoyan, et al.
Publicado: (2018)

Bruceine a exerts antitumor effect against colon cancer by accumulating ROS and suppressing PI3K/Akt pathway
por: Zhang, Chaozheng, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_8t2n3br4napcacd0g1mva9olio