Predominance of the heterozygous CCR5 delta‐24 deletion in African individuals resistant to HIV infection might be related to a defect in CCR5 addressing at the cell surface

INTRODUCTION: The chemokine receptor CCR5 is the main co‐receptor for R5‐tropic HIV‐1 variants. We have previously described a novel 24‐base pair deletion in the coding region of CCR5 among individuals from Rwanda. Here, we investigated the prevalence of hCCR5Δ24 in different cohorts and its impact...

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Detalles Bibliográficos
Autores principales: Arendt, Vic, Amand, Mathieu, Iserentant, Gilles, Lemaire, Morgane, Masquelier, Cécile, Ndayisaba, Gilles F, Verhofstede, Chris, Karita, Etienne, Allen, Susan, Chevigné, Andy, Schmit, Jean‐Claude, Bercoff, Danielle Perez, Seguin‐Devaux, Carole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Short Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727025/
https://www.ncbi.nlm.nih.gov/pubmed/31486251
http://dx.doi.org/10.1002/jia2.25384

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