Cargando…

Depalmitoylation by Palmitoyl-Protein Thioesterase 1 in Neuronal Health and Degeneration

Protein palmitoylation is the post-translational, reversible addition of a 16-carbon fatty acid, palmitate, to proteins. Protein palmitoylation has recently garnered much attention, as it robustly modifies the localization and function of canonical signaling molecules and receptors. Protein depalmit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Koster, Kevin P., Yoshii, Akira
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727029/ https://www.ncbi.nlm.nih.gov/pubmed/31555119 http://dx.doi.org/10.3389/fnsyn.2019.00025

Ejemplares similares

Identification of substrates of palmitoyl protein thioesterase 1 highlights roles of depalmitoylation in disulfide bond formation and synaptic function
por: Gorenberg, Erica L., et al.
Publicado: (2022)

The Interactome of Palmitoyl-Protein Thioesterase 1 (PPT1) Affects Neuronal Morphology and Function
por: Sapir, Tamar, et al.
Publicado: (2019)

Insights into the molecular basis of the palmitoylation and depalmitoylation of NCX1
por: Gök, Caglar, et al.
Publicado: (2021)

Editorial: Role of Protein Palmitoylation in Synaptic Plasticity and Neuronal Differentiation
por: Yoshii, Akira, et al.
Publicado: (2020)

Activity-dependent post-translational regulation of palmitoylating and depalmitoylating enzymes in the hippocampus
por: Abazari, Danya, et al.
Publicado: (2023)

Acyl-protein thioesterase1 alleviates senile osteoporosis by promoting osteoblast differentiation via depalmitoylation of BMPR1a
por: Ji, Changjiao, et al.
Publicado: (2023)

Glycosylation, transport, and complex formation of palmitoyl protein thioesterase 1 (PPT1) – distinct characteristics in neurons
por: Lyly, Annina, et al.
Publicado: (2007)

Reversible Cysteine Acylation Regulates the Activity of Human Palmitoyl-Protein Thioesterase 1 (PPT1)
por: Segal-Salto, Michal, et al.
Publicado: (2016)

Trypanosoma brucei Acyl-Protein Thioesterase-like (TbAPT-L) Is a Lipase with Esterase Activity for Short and Medium-Chain Fatty Acids but Has No Depalmitoylation Activity
por: Brown, Robert W. B., et al.
Publicado: (2022)

Palmitoyl Protein Thioesterase 1 Is Essential for Myogenic Autophagy of C2C12 Skeletal Myoblast
por: Yun, Hyeong Rok, et al.
Publicado: (2020)

Palmitoylated acyl protein thioesterase APT2 deforms membranes to extract substrate acyl chains
por: Abrami, Laurence, et al.
Publicado: (2021)

Enzymatic activity of palmitoyl‐protein thioesterase‐1 in serum from schizophrenia significantly associates with schizophrenia diagnosis scales
por: Wu, Yaoyao, et al.
Publicado: (2019)

Mice deficient in the lysosomal enzyme palmitoyl-protein thioesterase 1 (PPT1) display a complex retinal phenotype
por: Atiskova, Yevgeniya, et al.
Publicado: (2019)

Tandem Mass Spectrometry Assays of Palmitoyl Protein Thioesterase 1 and Tripeptidyl Peptidase Activity in Dried Blood Spots for the Detection of Neuronal Ceroid Lipofuscinoses in Newborns
por: Barcenas, Mariana, et al.
Publicado: (2014)

In a Model of Batten Disease, Palmitoyl Protein Thioesterase-1 Deficiency Is Associated with Brown Adipose Tissue and Thermoregulation Abnormalities
por: Khaibullina, Alfia, et al.
Publicado: (2012)

mTORC1 Signaling Is Palmitoylation-Dependent in Hippocampal Neurons and Non-neuronal Cells and Involves Dynamic Palmitoylation of LAMTOR1 and mTOR
por: Sanders, Shaun S., et al.
Publicado: (2019)

Construction of efficient and effective transformation vectors for palmitoyl-acyl carrier protein thioesterase gene silencing in oil palm
por: Bhore, Subhash Janardhan, et al.
Publicado: (2011)

Targeting MC1R depalmitoylation to prevent melanomagenesis in redheads
por: Chen, Shuyang, et al.
Publicado: (2019)

The Batten Disease Palmitoyl Protein Thioesterase 1 Gene Regulates Neural Specification and Axon Connectivity during Drosophila Embryonic Development
por: Chu-LaGraff, Quynh, et al.
Publicado: (2010)

Palmitoyltransferase DHHC9 and acyl protein thioesterase APT1 modulate renal fibrosis through regulating β-catenin palmitoylation
por: Gu, Mengru, et al.
Publicado: (2023)

Palmitoylated Proteins in Dendritic Spine Remodeling
por: Albanesi, Joseph P., et al.
Publicado: (2020)

Palmitoylation regulates neuropilin-2 localization and function in cortical neurons and conveys specificity to semaphorin signaling via palmitoyl acyltransferases
por: Koropouli, Eleftheria, et al.
Publicado: (2023)

Developmental NMDA receptor dysregulation in the infantile neuronal ceroid lipofuscinosis mouse model
por: Koster, Kevin P, et al.
Publicado: (2019)

Detection of Protein Palmitoylation in Cultured Hippocampal Neurons by Immunoprecipitation and Acyl-Biotin Exchange (ABE)
por: Brigidi, G. Stefano, et al.
Publicado: (2013)

Active and dynamic mitochondrial S-depalmitoylation revealed by targeted fluorescent probes
por: Kathayat, Rahul S., et al.
Publicado: (2018)

PPT1 regulation of HSP90α depalmitoylation participates in the pathogenesis of hyperandrogenism
por: Xue, Tongmin, et al.
Publicado: (2023)

A fluorescent probe for cysteine depalmitoylation reveals dynamic APT signaling
por: Kathayat, Rahul S., et al.
Publicado: (2016)

The Networks of Genes Encoding Palmitoylated Proteins in Axonal and Synaptic Compartments Are Affected in PPT1 Overexpressing Neuronal-Like Cells
por: Pezzini, Francesco, et al.
Publicado: (2017)

Role of Palmitoylation of Postsynaptic Proteins in Promoting Synaptic Plasticity
por: Matt, Lucas, et al.
Publicado: (2019)

Adult-Onset Neuronal Ceroid Lipofuscinosis With a Novel DNAJC5 Mutation Exhibits Aberrant Protein Palmitoylation
por: Huang, Qiang, et al.
Publicado: (2022)

Depalmitoylated Ras traffics to and from the Golgi complex via a nonvesicular pathway
por: Goodwin, J. Shawn, et al.
Publicado: (2005)

Neuronal activity moves protein palmitoylation into the synapse
por: Dalva, Matthew B.
Publicado: (2009)

Wogonoside induces depalmitoylation and translocation of PLSCR1 and N‐RAS in primary acute myeloid leukaemia cells
por: Li, Hui, et al.
Publicado: (2018)

S-palmitoylation Is Required for the Control of Growth Cone Morphology of DRG Neurons by CNP-Induced cGMP Signaling
por: Dumoulin, Alexandre, et al.
Publicado: (2018)

Syntaxin-1A modulates vesicle fusion in mammalian neurons via juxtamembrane domain dependent palmitoylation of its transmembrane domain
por: Vardar, Gülçin, et al.
Publicado: (2022)

Exploring the expression patterns of palmitoylating and de-palmitoylating enzymes in the mouse brain using the curated RNA-seq database BrainPalmSeq
por: Wild, Angela R, et al.
Publicado: (2022)

Development of an activity-based probe for acyl-protein thioesterases
por: Garland, Megan, et al.
Publicado: (2018)

Altered Regulation of Striatal Neuronal N-Methyl-D-Aspartate Receptor Trafficking by Palmitoylation in Huntington Disease Mouse Model
por: Kang, Rujun, et al.
Publicado: (2019)

S-Palmitoylation of Synaptic Proteins in Neuronal Plasticity in Normal and Pathological Brains
por: Buszka, Anna, et al.
Publicado: (2023)

Membrane palmitoylated protein 2 is a synaptic scaffold protein required for synaptic SK2-containing channel function
por: Kim, Gukhan, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_nu3mqfhrgemvpaogpvft1g4li2