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TRAF2 Controls Death Receptor-Induced Caspase-8 Processing and Facilitates Proinflammatory Signaling

Tumor necrosis factor (TNF) receptor associated factor-2 (TRAF2) knockout (KO) cells were generated to investigate the role of TRAF2 in signaling by TNFR1 and the CD95-type death receptors (DRs) TRAILR1/2 and CD95. To prevent negative selection effects arising from the increased cell death sensitivi...

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Detalles Bibliográficos
Autores principales:	Kreckel, Jennifer, Anany, Mohammed A., Siegmund, Daniela, Wajant, Harald
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727177/ https://www.ncbi.nlm.nih.gov/pubmed/31555268 http://dx.doi.org/10.3389/fimmu.2019.02024

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