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Impact of coronary artery disease on outcomes of severe aortic stenosis treatment with transcatheter aortic valve implantation
INTRODUCTION: The presence of coronary artery disease (CAD) in patients who underwent transcatheter aortic valve implantation (TAVI) may increase in-hospital and long-term mortality. AIM: To evaluate the impact of CAD in patients who underwent TAVI. MATERIAL AND METHODS: The study group consisted of...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Termedia Publishing House
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727222/ https://www.ncbi.nlm.nih.gov/pubmed/31497049 http://dx.doi.org/10.5114/aic.2019.84394 |
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author | Chodór, Piotr Wilczek, Krzysztof Włoch, Łukasz Przybylski, Roman Głowacki, Jan Kukulski, Tomasz Niklewski, Tomasz Zembala, Marian Gąsior, Mariusz Kalarus, Zbigniew |
author_facet | Chodór, Piotr Wilczek, Krzysztof Włoch, Łukasz Przybylski, Roman Głowacki, Jan Kukulski, Tomasz Niklewski, Tomasz Zembala, Marian Gąsior, Mariusz Kalarus, Zbigniew |
author_sort | Chodór, Piotr |
collection | PubMed |
description | INTRODUCTION: The presence of coronary artery disease (CAD) in patients who underwent transcatheter aortic valve implantation (TAVI) may increase in-hospital and long-term mortality. AIM: To evaluate the impact of CAD in patients who underwent TAVI. MATERIAL AND METHODS: The study group consisted of the first 142 patients treated with TAVI between 26 November 2008 and 31 December 2015. The patients were divided into two groups: group I comprised 103 (72.5%) patients with CAD, and group II comprised 39 (27.5%) patients without CAD. RESULTS: Group I was characterized by a significantly higher risk according to EuroSCORE – 11.2 ±2.5 vs. 9 ±2.3 in group II (p < 0.001) and Logistic EuroSCORE – 25.4 ±13.4 vs. 16.3 ±8.7 (p < 0.001). 30-day mortality was 8 (7.8%) vs. 2 (5.1%) (p = NS) and 1-year mortality was 22 (21.4%) vs. 6 (15.4%) (p = NS) in group I and II respectively. The composite endpoint evaluating the efficacy of TAVI was achieved in 82 (79.6%) vs. 31 (79.5%) (p = NS) in group I and II respectively. The composite endpoint, which involved 30-day observation, occurred in 39 (37.86%) vs. 12 (30.77%) (p = NS) and the composite endpoint, which involved 1-year evaluation of the clinical efficacy of TAVI, occurred in 48 (57.8%) vs. 13 (48.1%) (p = NS) in patients with and without CAD respectively. CONCLUSIONS: The short- and mid-term outcomes of TAVI patients with CAD, despite higher risk profile, did not differ from the outcomes of treatment in patients without CAD. |
format | Online Article Text |
id | pubmed-6727222 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Termedia Publishing House |
record_format | MEDLINE/PubMed |
spelling | pubmed-67272222019-09-06 Impact of coronary artery disease on outcomes of severe aortic stenosis treatment with transcatheter aortic valve implantation Chodór, Piotr Wilczek, Krzysztof Włoch, Łukasz Przybylski, Roman Głowacki, Jan Kukulski, Tomasz Niklewski, Tomasz Zembala, Marian Gąsior, Mariusz Kalarus, Zbigniew Postepy Kardiol Interwencyjnej Original Paper INTRODUCTION: The presence of coronary artery disease (CAD) in patients who underwent transcatheter aortic valve implantation (TAVI) may increase in-hospital and long-term mortality. AIM: To evaluate the impact of CAD in patients who underwent TAVI. MATERIAL AND METHODS: The study group consisted of the first 142 patients treated with TAVI between 26 November 2008 and 31 December 2015. The patients were divided into two groups: group I comprised 103 (72.5%) patients with CAD, and group II comprised 39 (27.5%) patients without CAD. RESULTS: Group I was characterized by a significantly higher risk according to EuroSCORE – 11.2 ±2.5 vs. 9 ±2.3 in group II (p < 0.001) and Logistic EuroSCORE – 25.4 ±13.4 vs. 16.3 ±8.7 (p < 0.001). 30-day mortality was 8 (7.8%) vs. 2 (5.1%) (p = NS) and 1-year mortality was 22 (21.4%) vs. 6 (15.4%) (p = NS) in group I and II respectively. The composite endpoint evaluating the efficacy of TAVI was achieved in 82 (79.6%) vs. 31 (79.5%) (p = NS) in group I and II respectively. The composite endpoint, which involved 30-day observation, occurred in 39 (37.86%) vs. 12 (30.77%) (p = NS) and the composite endpoint, which involved 1-year evaluation of the clinical efficacy of TAVI, occurred in 48 (57.8%) vs. 13 (48.1%) (p = NS) in patients with and without CAD respectively. CONCLUSIONS: The short- and mid-term outcomes of TAVI patients with CAD, despite higher risk profile, did not differ from the outcomes of treatment in patients without CAD. Termedia Publishing House 2019-04-09 2019 /pmc/articles/PMC6727222/ /pubmed/31497049 http://dx.doi.org/10.5114/aic.2019.84394 Text en Copyright: © 2019 Termedia Sp. z o. o. http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license. |
spellingShingle | Original Paper Chodór, Piotr Wilczek, Krzysztof Włoch, Łukasz Przybylski, Roman Głowacki, Jan Kukulski, Tomasz Niklewski, Tomasz Zembala, Marian Gąsior, Mariusz Kalarus, Zbigniew Impact of coronary artery disease on outcomes of severe aortic stenosis treatment with transcatheter aortic valve implantation |
title | Impact of coronary artery disease on outcomes of severe aortic stenosis treatment with transcatheter aortic valve implantation |
title_full | Impact of coronary artery disease on outcomes of severe aortic stenosis treatment with transcatheter aortic valve implantation |
title_fullStr | Impact of coronary artery disease on outcomes of severe aortic stenosis treatment with transcatheter aortic valve implantation |
title_full_unstemmed | Impact of coronary artery disease on outcomes of severe aortic stenosis treatment with transcatheter aortic valve implantation |
title_short | Impact of coronary artery disease on outcomes of severe aortic stenosis treatment with transcatheter aortic valve implantation |
title_sort | impact of coronary artery disease on outcomes of severe aortic stenosis treatment with transcatheter aortic valve implantation |
topic | Original Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727222/ https://www.ncbi.nlm.nih.gov/pubmed/31497049 http://dx.doi.org/10.5114/aic.2019.84394 |
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