Cargando…
Synthesis and exploration of a novel chlorobenzylated 2-aminothiazole-phenyltriazole hybrid as migratory inhibitor of B16F10 in melanoma cells
In the study presented here, a novel chlorobenzylated bi-heterocyclic hybrid molecule (7) was synthesized and its structural confirmation was carried out by IR, (1)H-NMR, (13)C-NMR and CHN analysis data. This compound 7 was subjected to biological study with B16F10 mouse melanoma cells. The anti-pro...
Autores principales: | Athar Abbasi, Muhammad, Yu, Seon-Mi, Aziz-ur-Rehman, Siddiqui, Sabahat Zahra, Kim, Song Ja, Raza, Hussain, Hassan, Mubashir, Rehman Sadiq Butt, Abdul, Shah, Syed Adnan Ali, Seo, Sung-Yum |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727243/ https://www.ncbi.nlm.nih.gov/pubmed/31516842 http://dx.doi.org/10.1016/j.toxrep.2019.08.016 |
Ejemplares similares
-
Synthesis, Kinetics, Binding Conformations and Structure-activity Relationship of Potent Tyrosinase Inhibitors: Aralkylated 2-aminothiazole-ethyltriazole Hybrids
por: Sadiq Butt, Abdul Rehman, et al.
Publicado: (2021) -
Synthesis, enzyme inhibitory kinetics mechanism and computational study of N-(4-methoxyphenethyl)-N-(substituted)-4-methylbenzenesulfonamides as novel therapeutic agents for Alzheimer’s disease
por: Abbasi, Muhammad Athar, et al.
Publicado: (2018) -
Novel indole based hybrid oxadiazole scaffolds with N-(substituted-phenyl)butanamides: synthesis, lineweaver–burk plot evaluation and binding analysis of potent urease inhibitors
por: Nazir, Majid, et al.
Publicado: (2018) -
Convergent synthesis, kinetics insight and allosteric computational ascriptions of thiazole-(5-aryl)oxadiazole hybrids embraced with propanamides as alkaline phosphatase inhibitors
por: Butt, Abdul Rehman Sadiq, et al.
Publicado: (2023) -
Synthesis and Molecular Docking Studies of Novel Biheterocyclic
Propanamides as Antidiabetic Agents Having Mild Cytotoxicity
por: Abbasi, Muhammad Athar, et al.
Publicado: (2023)