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Combined targeting of HER-2 and HER-3 represents a promising therapeutic strategy in colorectal cancer

BACKGROUND: Abrogation of growth factor-dependent signaling represents an effective therapeutic strategy for patients with colorectal cancer (CRC). Here we evaluated the effectiveness of targeting the epidermal growth factor (EGF) receptors HER-2 and HER-3 in the three cell lines LS513, LS1034 and S...

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Detalles Bibliográficos
Autores principales:	Conradi, Lena-Christin, Spitzner, Melanie, Metzger, Anna-Lena, Kisly, Merle, Middel, Peter, Bohnenberger, Hanibal, Gaedcke, Jochen, Ghadimi, Michael B., Liersch, Torsten, Rüschoff, Joseph, Beißbarth, Tim, König, Alexander, Grade, Marian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727342/ https://www.ncbi.nlm.nih.gov/pubmed/31488078 http://dx.doi.org/10.1186/s12885-019-6051-0

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