Intracellular human antibody fragments recognizing the VP35 protein of Zaire Ebola filovirus inhibit the protein activity

BACKGROUND: Ebola hemorrhagic fever is caused by the Ebola filovirus (EBOV), which is one of the most aggressive infectious agents known worldwide. The EBOV pathogenesis starts with uncontrolled viral replication and subversion of both the innate and adaptive host immune response. The multifunctiona...

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Detalles Bibliográficos
Autores principales: Flego, Michela, Frau, Aldo, Accardi, Luisa, Mallano, Alessandra, Ascione, Alessandro, Gellini, Mara, Fanunza, Elisa, Vella, Stefano, Di Bonito, Paola, Tramontano, Enzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727353/
https://www.ncbi.nlm.nih.gov/pubmed/31488108
http://dx.doi.org/10.1186/s12896-019-0554-2

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