Cargando…

Knockdown of circDENND4C inhibits glycolysis, migration and invasion by up-regulating miR-200b/c in breast cancer under hypoxia

BACKGROUND: Hypoxia is a key feature of breast cancer, which affects cancer development, metastasis and metabolism. Previous studies suggested that circular RNAs (circRNAs) could participate in cancer progression and hypoxia regulation. This study aimed to investigate the role of circRNA differentia...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ren, Shasha, Liu, Jiuzhou, Feng, Yun, Li, Zhenyu, He, Liang, Li, Leilei, Cao, Xiaozhong, Wang, Zhenghua, Zhang, Yanwu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727545/ https://www.ncbi.nlm.nih.gov/pubmed/31488193 http://dx.doi.org/10.1186/s13046-019-1398-2

Ejemplares similares

circDENND4C Promotes Proliferation and Metastasis of Lung Cancer by Upregulating BRD4 Signaling Pathway
por: Ma, Dongjie, et al.
Publicado: (2021)

Hypoxia-associated circDENND2A promotes glioma aggressiveness by sponging miR-625-5p
por: Su, Hui, et al.
Publicado: (2019)

CircDENND2A Promotes Non-small Cell Lung Cancer Progression via Regulating MiR-34a/CCNE1 Signaling
por: Zhang, Yinbin, et al.
Publicado: (2020)

Tumor-Associated Fibroblast-Derived Exosomal circDennd1b Promotes Pituitary Adenoma Progression by Modulating the miR-145-5p/ONECUT2 Axis and Activating the MAPK Pathway
por: Jiang, Qian, et al.
Publicado: (2023)

circDENND1B Participates in the Antiatherosclerotic Effect of IL-1β Monoclonal Antibody in Mouse by Promoting Cholesterol Efflux via miR-17-5p/Abca1 Axis
por: Xu, Fei, et al.
Publicado: (2021)

Hypoxia-induced circRNF13 promotes the progression and glycolysis of pancreatic cancer
por: Zhao, Qiuyan, et al.
Publicado: (2022)

Connecdenn 3/DENND1C binds actin linking Rab35 activation to the actin cytoskeleton
por: Marat, Andrea L., et al.
Publicado: (2012)

KHDRBS3 regulates the permeability of blood–tumor barrier via cDENND4C/miR-577 axis
por: Wu, Peiqi, et al.
Publicado: (2019)

Circ-DENND4C up-regulates TCF4 expression to modulate hepatocellular carcinoma cell proliferation and apoptosis via activating Wnt/β-catenin signal pathway
por: Liu, Xialei, et al.
Publicado: (2020)

Knockdown of MicroRNA-122 Protects H9c2 Cardiomyocytes from Hypoxia-Induced Apoptosis and Promotes Autophagy
por: Zhang, Zaiwei, et al.
Publicado: (2017)

CircNFIC Balances Inflammation and Apoptosis by Sponging miR-30e-3p and Regulating DENND1B Expression
por: Chen, Yangfeng, et al.
Publicado: (2021)

Retraction Note to: Circ-DENND4C up-regulates TCF4 expression to modulate hepatocellular carcinoma cell proliferation and apoptosis via activating Wnt/β-catenin signal pathway
por: Liu, Xialei, et al.
Publicado: (2021)

Retracted: Knockdown of MicroRNA-122 Protects H9c2 Cardiomyocytes from Hypoxia-Induced Apoptosis and Promotes Autophagy
por: Zhang, Zaiwei, et al.
Publicado: (2021)

DENND5B Regulates Intestinal Triglyceride Absorption and Body Mass
por: Gordon, Scott M., et al.
Publicado: (2019)

DENND2B activates Rab13 at the leading edge of migrating cells and promotes metastatic behavior
por: Ioannou, Maria S., et al.
Publicado: (2015)

circRNA DENND1B inhibits tumorigenicity of clear cell renal cell carcinoma via miR-122-5p/TIMP2 axis
por: Chen, Deqiang, et al.
Publicado: (2022)

Knockdown of the TP53-Induced Glycolysis and Apoptosis Regulator (TIGAR) Sensitizes Glioma Cells to Hypoxia, Irradiation and Temozolomide
por: Maurer, Gabriele D., et al.
Publicado: (2019)

Knockdown of circEXOC6 inhibits cell progression and glycolysis by sponging miR-433-3p and mediating FZD6 in glioma
por: Deng, Yu, et al.
Publicado: (2023)

CircC6orf132 Facilitates Proliferation, Migration, Invasion, and Glycolysis of Gastric Cancer Cells Under Hypoxia by Acting on the miR-873-5p/PRKAA1 Axis
por: Chen, Weizhi, et al.
Publicado: (2021)

Hsa_circ_0000069 Knockdown Inhibits Tumorigenesis and Exosomes with Downregulated hsa_circ_0000069 Suppress Malignant Transformation via Inhibition of STIL in Pancreatic Cancer
por: Ye, Zhenyu, et al.
Publicado: (2020)

Tip of the Iceberg: Roles of CircRNAs in Cancer Glycolysis
por: Li, Tan, et al.
Publicado: (2021)

Association of DENND1A Gene Polymorphisms with Polycystic Ovary Syndrome: A Meta-Analysis
por: Bao, Shan, et al.
Publicado: (2016)

Hsa_circ_0000231 knockdown inhibits the glycolysis and progression of colorectal cancer cells by regulating miR-502-5p/MYO6 axis
por: Liu, Yanhe, et al.
Publicado: (2020)

CircASXL1 Knockdown Restrains Hypoxia-Induced DDP Resistance and NSCLC Progression by Sponging miR-206
por: Yu, Liuyang, et al.
Publicado: (2021)

Knockdown of hsa_circ_0008922 inhibits the progression of glioma
por: Xue, Chunhong, et al.
Publicado: (2022)

Genetic Alterations within the DENND1A Gene in Patients with Polycystic Ovary Syndrome (PCOS)
por: Eriksen, Mette B., et al.
Publicado: (2013)

Association of FSHR and DENND1A polymorphisms with polycystic ovary syndrome: a meta-analysis
por: Larsen, Celina Bakke, et al.
Publicado: (2023)

Cancer driver candidate genes AVL9, DENND5A and NUPL1 contribute to MDCK cystogenesis
por: Li, Yaping, et al.
Publicado: (2014)

CircCDK17 knockdown inhibits tumor progression and cell glycolysis by downregulaing YWHAZ expression through sponging miR-1294 in cervical cancer
por: Chen, Rui, et al.
Publicado: (2022)

Knockdown of circADAM9 inhibits cell progression and glycolysis by targeting the miR‐1236‐3p/FGF7 axis in breast cancer
por: Huang, Bo, et al.
Publicado: (2023)

EGF Stimulates Rab35 Activation and Gastric Cancer Cell Migration by Regulating DENND1A-Grb2 Complex Formation
por: Ye, Bixing, et al.
Publicado: (2018)

Circ_0062020 Knockdown Strengthens the Radiosensitivity of Prostate Cancer Cells
por: Li, Haitao, et al.
Publicado: (2020)

PlGF knockdown attenuates hypoxia-induced stimulation of cell proliferation and glycolysis of lung adenocarcinoma through inhibiting Wnt/β-catenin pathway
por: Zhang, Wei, et al.
Publicado: (2021)

Circular RNA circPITX1 knockdown inhibits glycolysis to enhance radiosensitivity of glioma cells by miR-329-3p/NEK2 axis
por: Guan, Yongchang, et al.
Publicado: (2020)

Circular RNA circ_0061140 accelerates hypoxia-induced glycolysis, migration, and invasion in lung adenocarcinoma through the microRNA-653/hexokinase 2 (HK2) axis
por: Wang, Shaobin, et al.
Publicado: (2022)

Hsa_circ_0128846 knockdown attenuates the progression of pancreatic cancer by targeting miR-1270/NR3C1 axis
por: Wang, Ming, et al.
Publicado: (2023)

Hypoxia-induced exosomal circPDK1 promotes pancreatic cancer glycolysis via c-myc activation by modulating miR-628-3p/BPTF axis and degrading BIN1
por: Lin, Jiewei, et al.
Publicado: (2022)

CircASXL1 Knockdown Restrains Hypoxia-Induced DDP Resistance and NSCLC Progression by Sponging miR-206 [Retraction]
Publicado: (2022)

Knockdown of lncRNA NEAT1 suppresses hypoxia-induced migration, invasion and glycolysis in anaplastic thyroid carcinoma cells through regulation of miR-206 and miR-599
por: Tan, Xiangrong, et al.
Publicado: (2020)

DOCK11 and DENND2A play pivotal roles in the maintenance of hepatitis B virus in host cells
por: Hashimoto, Shinichi, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_9m5m43blln4qjhlc0gdf9ucc8f