Hypoxic exosomes facilitate angiogenesis and metastasis in esophageal squamous cell carcinoma through altering the phenotype and transcriptome of endothelial cells

BACKGROUND: In cancer progression, hypoxia, or low oxygen tension, is a major regulator of tumor aggressiveness and metastasis. However, how cancer cells adapt to the hypoxia and communicate with other mesenchymal cells in microenvironment during tumor development remains to be elucidated. Here, we...

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Detalles Bibliográficos
Autores principales: Mao, Yu, Wang, Yimin, Dong, Lixin, Zhang, Yunjie, Zhang, Yanqiu, Wang, Chao, Zhang, Qiang, Yang, Sen, Cao, Liyan, Zhang, Xinyuan, Li, Xin, Fu, Zhanzhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727585/
https://www.ncbi.nlm.nih.gov/pubmed/31488217
http://dx.doi.org/10.1186/s13046-019-1384-8

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