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Pinacol-Derived Chlorohydrosilane in Metal-Free Reductive Amination for the Preparation of Tertiary Alkylphenolmethyl Amines
[Image: see text] A new metal-free reductive amination protocol using a pinacol-derived chlorohydrosilane/pyridine system for the preparation of aminoalkylphenols is described. This method is selective toward iminiums derived from alkylphenol ketones under an in situ formation of a trialkoxyhydrosil...
Autores principales: | Assoah, Benedicta, Veiros, Luis F., Candeias, Nuno R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2019
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727611/ https://www.ncbi.nlm.nih.gov/pubmed/30767545 http://dx.doi.org/10.1021/acs.orglett.9b00121 |
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