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The structural and gene expression hypotheses in laminopathic diseases—not so different after all
Laminopathies are a diverse group of rare diseases with various pathologies in different tissues, which are linked to mutations in the LMNA gene. Historically, the structural disease model proposed mechanical defects of the lamina and nuclear fragility, the gene expression model impairment of spatia...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727745/ https://www.ncbi.nlm.nih.gov/pubmed/31306095 http://dx.doi.org/10.1091/mbc.E18-10-0672 |