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Ablation of SUN2-containing LINC complexes drives cardiac hypertrophy without interstitial fibrosis
The cardiomyocyte cytoskeleton, including the sarcomeric contractile apparatus, forms a cohesive network with cellular adhesions at the plasma membrane and nuclear–cytoskeletal linkages (LINC complexes) at the nuclear envelope. Human cardiomyopathies are genetically linked to the LINC complex and A...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727752/ https://www.ncbi.nlm.nih.gov/pubmed/31091167 http://dx.doi.org/10.1091/mbc.E18-07-0438 |