Cargando…

Ablation of SUN2-containing LINC complexes drives cardiac hypertrophy without interstitial fibrosis

The cardiomyocyte cytoskeleton, including the sarcomeric contractile apparatus, forms a cohesive network with cellular adhesions at the plasma membrane and nuclear–cytoskeletal linkages (LINC complexes) at the nuclear envelope. Human cardiomyopathies are genetically linked to the LINC complex and A...

Descripción completa

Detalles Bibliográficos
Autores principales:	Stewart, Rachel M., Rodriguez, Elisa C., King, Megan C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727752/ https://www.ncbi.nlm.nih.gov/pubmed/31091167 http://dx.doi.org/10.1091/mbc.E18-07-0438

Ejemplares similares

Treatment of myocardial interstitial fibrosis in pathological myocardial hypertrophy
por: Zhu, Fuyu, et al.
Publicado: (2022)

Cellular hypertrophy occurs before interstitial fibrosis in pressure-overload heart failure
por: Shah, Ravi, et al.
Publicado: (2013)

Cardiac Magnetic Resonance Assessment of Interstitial Myocardial Fibrosis and Cardiomyocyte Hypertrophy in Hypertensive Mice Treated With Spironolactone
por: Coelho‐Filho, Otavio R., et al.
Publicado: (2014)

Postnatal Ablation of Foxm1 from Cardiomyocytes Causes Late Onset Cardiac Hypertrophy and Fibrosis without Exacerbating Pressure Overload-Induced Cardiac Remodeling
por: Bolte, Craig, et al.
Publicado: (2012)

The mammalian LINC complex component SUN1 regulates muscle regeneration by modulating drosha activity
por: Loo, Tsui Han, et al.
Publicado: (2019)

Non-invasive assessment of interstitial myocardial fibrosis in pressure-overload left ventricular hypertrophy
por: Jabbour, Andrew, et al.
Publicado: (2012)

Left ventricular hypertrophy with cardiomyocyte atrophy and extensive interstitial fibrosis: a mitochondrial cardiomyopathy
por: Zhang, Xinyu, et al.
Publicado: (2022)

Lipedema stage affects adipocyte hypertrophy, subcutaneous adipose tissue inflammation and interstitial fibrosis
por: Kruppa, Philipp, et al.
Publicado: (2023)

Evidence for LINC1-SUN Associations at the Plant Nuclear Periphery
por: Graumann, Katja
Publicado: (2014)

Immobilizing Interstitial Cardiac Fibrosis
por: Shevchenko, Yuriy L., et al.
Publicado: (2023)

The LINC complex transmits integrin-dependent tension to the nuclear lamina and represses epidermal differentiation
por: Carley, Emma, et al.
Publicado: (2021)

Identification of circular RNAs in cardiac hypertrophy and cardiac fibrosis
por: Chen, Yan, et al.
Publicado: (2022)

Hydrogen-containing saline alleviates pressure overload-induced interstitial fibrosis and cardiac dysfunction in rats
por: Yang, Jing, et al.
Publicado: (2017)

A molecular model for LINC complex regulation: activation of SUN2 for KASH binding
por: Jahed, Zeinab, et al.
Publicado: (2018)

Cardiac‐specific ablation of glutaredoxin 3 leads to cardiac hypertrophy and heart failure
por: Donelson, Jimmonique, et al.
Publicado: (2019)

Differential incorporation of SUN-domain proteins into LINC complexes is coupled to gene expression
por: May, Christopher K., et al.
Publicado: (2018)

Parahippocampus hypertrophy drives gray matter morphological alterations in migraine patients without aura
por: Yin, Tao, et al.
Publicado: (2023)

Overview of MicroRNAs in Cardiac Hypertrophy, Fibrosis, and Apoptosis
por: Wang, Juan, et al.
Publicado: (2016)

Interstitial expansion in pressure overload left ventricular hypertrophy
por: Treibel, Thomas A, et al.
Publicado: (2013)

Disulfide bond in SUN2 regulates dynamic remodeling of LINC complexes at the nuclear envelope
por: Sharma, Rahul, et al.
Publicado: (2023)

Biowire Model of Interstitial and Focal Cardiac Fibrosis
por: Wang, Erika Yan, et al.
Publicado: (2019)

Linking LOXL2 to Cardiac Interstitial Fibrosis
por: Erasmus, Melisse, et al.
Publicado: (2020)

SUN-368 Fatty Hypertrophy of the Hip as a Clinical Manifestation of Cushing Syndrome
por: McGlotten, Raven, et al.
Publicado: (2019)

Bezafibrate Attenuates Pressure Overload-Induced Cardiac Hypertrophy and Fibrosis
por: Xu, Si-Chi, et al.
Publicado: (2017)

Analysis of Meiosis in SUN1 Deficient Mice Reveals a Distinct Role of SUN2 in Mammalian Meiotic LINC Complex Formation and Function
por: Link, Jana, et al.
Publicado: (2014)

Global PIEZO1 Gain-of-Function Mutation Causes Cardiac Hypertrophy and Fibrosis in Mice
por: Bartoli, Fiona, et al.
Publicado: (2022)

Sun StorageTek T9940 Tape Drive
Publicado: (2002)

Sun proteins and Dpy19l2 forming LINC-like links are critical for spermiogenesis
por: Ray, Pierre F., et al.
Publicado: (2016)

The SUN2-nesprin-2 LINC complex and KIF20A function in the Golgi dispersal
por: Hieda, Miki, et al.
Publicado: (2021)

Endomyocardial Fibrosis, Apical Hypertrophy, or Both?
por: Sehly, Amro, et al.
Publicado: (2022)

AN EXPERIMENTAL CONTRIBUTION TO THE STUDY OF CARDIAC HYPERTROPHY
por: Stewart, Hugh A.
Publicado: (1911)

Cardiac Expression of Factor X Mediates Cardiac Hypertrophy and Fibrosis in Pressure Overload
por: Guo, Xinji, et al.
Publicado: (2020)

Cardiac Expression of Factor X Mediates Cardiac Hypertrophy and Fibrosis in Pressure Overload
Publicado: (2022)

IKKi Deficiency Promotes Pressure Overload-Induced Cardiac Hypertrophy and Fibrosis
por: Dai, Jia, et al.
Publicado: (2013)

The LINC complex component Sun4 plays a crucial role in sperm head formation and fertility
por: Pasch, Elisabeth, et al.
Publicado: (2015)

Nuclear Envelope Retention of LINC Complexes Is Promoted by SUN-1 Oligomerization in the Caenorhabditis elegans Germ Line
por: Daryabeigi, Anahita, et al.
Publicado: (2016)

A molecular mechanism for LINC complex branching by structurally diverse SUN-KASH 6:6 assemblies
por: Gurusaran, Manickam, et al.
Publicado: (2021)

Global loss of a nuclear lamina component, lamin A/C, and LINC complex components SUN1, SUN2, and nesprin-2 in breast cancer
por: Matsumoto, Ayaka, et al.
Publicado: (2015)

SUN-516 Unplanned Pregnancy Post Thyroid RAI Ablation
por: Bhalodkar, Arpita, et al.
Publicado: (2020)

Interstitial fibrosis and growth factors.
por: Lasky, J A, et al.
Publicado: (2000)

Cannot write session to /tmp/vufind_sessions/sess_nggsq927tq6hin7h6c6nt96mv1