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Ablation of SUN2-containing LINC complexes drives cardiac hypertrophy without interstitial fibrosis

The cardiomyocyte cytoskeleton, including the sarcomeric contractile apparatus, forms a cohesive network with cellular adhesions at the plasma membrane and nuclear–cytoskeletal linkages (LINC complexes) at the nuclear envelope. Human cardiomyopathies are genetically linked to the LINC complex and A...

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Detalles Bibliográficos
Autores principales:	Stewart, Rachel M., Rodriguez, Elisa C., King, Megan C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727752/ https://www.ncbi.nlm.nih.gov/pubmed/31091167 http://dx.doi.org/10.1091/mbc.E18-07-0438

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