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The Drosophila Afadin and ZO-1 homologues Canoe and Polychaetoid act in parallel to maintain epithelial integrity when challenged by adherens junction remodeling
During morphogenesis, cells must change shape and move without disrupting tissue integrity. This requires cell–cell junctions to allow dynamic remodeling while resisting forces generated by the actomyosin cytoskeleton. Multiple proteins play roles in junctional–cytoskeletal linkage, but the mechanis...
Autores principales: | Manning, Lathiena A., Perez-Vale, Kia Z., Schaefer, Kristina N., Sewell, Mycah T., Peifer, Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727765/ https://www.ncbi.nlm.nih.gov/pubmed/31188739 http://dx.doi.org/10.1091/mbc.E19-04-0209 |
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