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Mechanical feedback enables catch bonds to selectively stabilize scanning microvilli at T-cell surfaces
T-cells use microvilli to search the surfaces of antigen-presenting cells for antigenic ligands. The active motion of scanning microvilli provides a force-generating mechanism that is intriguing in light of single-molecule experiments showing that applied forces increase the lifetimes of stimulatory...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727777/ https://www.ncbi.nlm.nih.gov/pubmed/31116687 http://dx.doi.org/10.1091/mbc.E19-01-0048 |