Glycoproteomic Analysis of the Aortic Extracellular Matrix in Marfan Patients

Marfan syndrome (MFS) is caused by mutations in FBN1 (fibrillin-1), an extracellular matrix (ECM) component, which is modified post-translationally by glycosylation. This study aimed to characterize the glycoproteome of the aortic ECM from patients with MFS and relate it to aortopathy. APPROACH AND...

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Detalles Bibliográficos
Autores principales: Yin (殷晓科), Xiaoke, Wanga, Shaynah, Fellows, Adam L., Barallobre-Barreiro, Javier, Lu, Ruifang, Davaapil, Hongorzul, Franken, Romy, Fava, Marika, Baig, Ferheen, Skroblin, Philipp, Xing, Qiuru, Koolbergen, David R., Groenink, Maarten, Zwinderman, Aeilko H., Balm, Ron, de Vries, Carlie J.M., Mulder, Barbara J.M., Viner, Rosa, Jahangiri, Marjan, Reinhardt, Dieter P., Sinha, Sanjay, de Waard, Vivian, Mayr, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2019
Materias:
Translational Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727943/
https://www.ncbi.nlm.nih.gov/pubmed/31315432
http://dx.doi.org/10.1161/ATVBAHA.118.312175

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