Cargando…

Identification of a Promiscuous Epitope Peptide Derived From HSP70

We previously found that heat-shock protein 70 (HSP70) is expressed on hepatocellular carcinoma cells and developed an HSP70 mRNA-transfected dendritic cell therapy for treating unresectable or recurrent hepatocellular carcinoma. The phase I trial was completed successfully. The purpose of this stud...

Descripción completa

Detalles Bibliográficos
Autores principales:	Matsui, Hiroto, Hazama, Shoichi, Tamada, Koji, Udaka, Keiko, Irie, Atsushi, Nishimura, Yasuharu, Miyakawa, Tomoya, Doi, Shun, Nakajima, Masao, Kanekiyo, Shinsuke, Tokumitsu, Yukio, Shindo, Yoshitaro, Tomochika, Shinobu, Yoshida, Shin, Iida, Michihisa, Suzuki, Nobuaki, Takeda, Shigeru, Yamamoto, Shigeru, Yoshino, Shigefumi, Ueno, Tomio, Nagano, Hiroaki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2019
Materias:	Basic Studies
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6727952/ https://www.ncbi.nlm.nih.gov/pubmed/31398179 http://dx.doi.org/10.1097/CJI.0000000000000274

Ejemplares similares

A phase I study of multi-HLA-binding peptides derived from heat shock protein 70/glypican-3 and a novel combination adjuvant of hLAG-3Ig and Poly-ICLC for patients with metastatic gastrointestinal cancers: YNP01 trial
por: Nakajima, Masao, et al.
Publicado: (2020)

Cetuximab strongly enhances immune cell infiltration into liver metastatic sites in colorectal cancer
por: Inoue, Yuka, et al.
Publicado: (2017)

Determining the protective characteristics and risk factors for the development of anastomotic leakage after low anterior resection for rectal cancer
por: Suzuki, Nobuaki, et al.
Publicado: (2020)

Laparoscopic Sutureless Rectopexy Using a Fixation Device for Complete Rectal Prolapse
por: Tomochika, Shinobu, et al.
Publicado: (2021)

Intratumoural-infiltrating CD4 + and FOXP3 + T cells as strong positive predictive markers for the prognosis of resectable colorectal cancer
por: Kuwahara, Taichi, et al.
Publicado: (2019)

Correction: Intratumoural-infiltrating CD4 + and FOXP3 + T cells as strong positive predictive markers for the prognosis of resectable colorectal cancer
por: Kuwahara, Taichi, et al.
Publicado: (2019)

Efficacy of intraoperative recurrent laryngeal neuromonitoring during surgery for esophageal cancer
por: Takeda, Shigeru, et al.
Publicado: (2020)

Postoperative Adjuvant Therapy for Resectable Pancreatic Cancer With Gemcitabine and Adoptive Immunotherapy
por: Matsui, Hiroto, et al.
Publicado: (2017)

A Phase I Clinical Trial of Vaccination With KIF20A-derived Peptide in Combination With Gemcitabine For Patients With Advanced Pancreatic Cancer
por: Suzuki, Nobuaki, et al.
Publicado: (2014)

Prediction of the efficacy of immunotherapy by measuring the integrity of cell‐free DNA in plasma in colorectal cancer
por: Kitahara, Masahiro, et al.
Publicado: (2016)

miR‐125b‐1 and miR‐378a are predictive biomarkers for the efficacy of vaccine treatment against colorectal cancer
por: Tanaka, Hironori, et al.
Publicado: (2017)

Pancreatic Cancer Stem-Like Cells With High Calreticulin Expression Associated With Immune Surveillance
por: Fujiwara, Yasuhiro, et al.
Publicado: (2021)

Elevated expression of RAB3B plays important roles in chemoresistance and metastatic potential of hepatoma cells
por: Tsunedomi, Ryouichi, et al.
Publicado: (2022)

CD4 and FOXP3 as predictive markers for the recurrence of T3/T4a stage II colorectal cancer: applying a novel discrete Bayes decision rule
por: Nakagami, Yuki, et al.
Publicado: (2022)

Siglec-7 is a predictive biomarker for the efficacy of cancer vaccination against metastatic colorectal cancer
por: Yamada, Kensuke, et al.
Publicado: (2021)

Adoptive immunotherapy with MUC1-mRNA transfected dendritic cells and cytotoxic lymphocytes plus gemcitabine for unresectable pancreatic cancer
por: Shindo, Yoshitaro, et al.
Publicado: (2014)

Association between a single nucleotide polymorphism in the R3HCC1 gene and irinotecan toxicity
por: Kanesada, Kou, et al.
Publicado: (2022)

Metastatic ability and the epithelial‐mesenchymal transition in induced cancer stem‐like hepatoma cells
por: Nishiyama, Mitsuo, et al.
Publicado: (2018)

MicroRNA-6826 and −6875 in plasma are valuable non-invasive biomarkers that predict the efficacy of vaccine treatment against metastatic colorectal cancer
por: Kijima, Taiki, et al.
Publicado: (2017)

Laparoscopic total biopsy for suspected gallbladder cancer: A case series
por: Tokumitsu, Yukio, et al.
Publicado: (2020)

Outcomes following liver resection for multinodular Barcelona Clinic Liver Cancer-B hepatocellular carcinoma
por: Matsukuma, Satoshi, et al.
Publicado: (2018)

miR-196b, miR-378a and miR-486 are predictive biomarkers for the efficacy of vaccine treatment in colorectal cancer
por: Shindo, Yoshitaro, et al.
Publicado: (2017)

The effect of the visceral fat area on the predictive accuracy of C‐reactive protein for infectious complications after laparoscopy‐assisted gastrectomy
por: Iida, Michihisa, et al.
Publicado: (2020)

High secreted protein acidic and rich in cysteine expression in peritumoral fibroblasts predicts better prognosis in patients with resectable gastric cancer
por: Nakajima, Masao, et al.
Publicado: (2018)

Perioperative Microbiologic Monitoring of Sputum on Postoperative Day One as a Predictor of Pneumonia After Hepatectomy
por: Sakamoto, Kazuhiko, et al.
Publicado: (2015)

Predictive biomarkers for the efficacy of peptide vaccine treatment: based on the results of a phase II study on advanced pancreatic cancer
por: Shindo, Yoshitaro, et al.
Publicado: (2017)

A novel prediction model of pancreatic fistula after pancreaticoduodenectomy using only preoperative markers
por: Matsui, Hiroto, et al.
Publicado: (2023)

Novel Biomarkers for Personalized Cancer Immunotherapy
por: Shindo, Yoshitaro, et al.
Publicado: (2019)

A stem cell medium containing neural stimulating factor induces a pancreatic cancer stem-like cell-enriched population
por: WATANABE, YUSAKU, et al.
Publicado: (2014)

Phase II clinical trial of peptide cocktail therapy for patients with advanced pancreatic cancer: VENUS‐PC study
por: Suzuki, Nobuaki, et al.
Publicado: (2016)

Characterization of the T cell repertoire by deep T cell receptor sequencing in tissues and blood from patients with advanced colorectal cancer
por: TAMURA, KENJI, et al.
Publicado: (2016)

Viral elimination is essential for improving surgical outcomes of hepatitis C virus‐related hepatocellular carcinoma: Multicenter retrospective analysis
por: Nakajima, Masao, et al.
Publicado: (2020)

Cathepsin B is highly expressed in pancreatic cancer stem-like cells and is associated with patients' surgical outcomes
por: Fujimoto, Takuya, et al.
Publicado: (2021)

Risk factors for non‐gastric‐cancer‐related death after gastrectomy in elderly patients
por: Iida, Michihisa, et al.
Publicado: (2022)

Essential updates to the surgical treatment of biliary tract cancer
por: Matsukuma, Satoshi, et al.
Publicado: (2019)

Expression levels of UL16 binding protein 1 and natural killer group 2 member D affect overall survival in patients with gastric cancer following gastrectomy
por: Kamei, Ryoji, et al.
Publicado: (2018)

Combined adjuvants of poly(I:C) plus LAG‐3‐Ig improve antitumor effects of tumor‐specific T cells, preventing their exhaustion
por: Kano, Yosuke, et al.
Publicado: (2016)

Calreticulin is highly expressed in pancreatic cancer stem‐like cells
por: Matsukuma, Satoshi, et al.
Publicado: (2016)

A phase ΙI study of five peptides combination with oxaliplatin-based chemotherapy as a first-line therapy for advanced colorectal cancer (FXV study)
por: Hazama, Shoichi, et al.
Publicado: (2014)

A novel system for predicting the toxicity of irinotecan based on statistical pattern recognition with UGT1A genotypes
por: TSUNEDOMI, RYOUICHI, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_27n9gppt0kehriogmo8mbj1ob7