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Evolution of intron splicing towards optimized gene expression is based on various Cis- and Trans-molecular mechanisms
Splicing expands, reshapes, and regulates the transcriptome of eukaryotic organisms. Despite its importance, key questions remain unanswered, including the following: Can splicing evolve when organisms adapt to new challenges? How does evolution optimize inefficiency of introns’ splicing and of the...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728054/ https://www.ncbi.nlm.nih.gov/pubmed/31442222 http://dx.doi.org/10.1371/journal.pbio.3000423 |