Evolution of intron splicing towards optimized gene expression is based on various Cis- and Trans-molecular mechanisms

Splicing expands, reshapes, and regulates the transcriptome of eukaryotic organisms. Despite its importance, key questions remain unanswered, including the following: Can splicing evolve when organisms adapt to new challenges? How does evolution optimize inefficiency of introns’ splicing and of the...

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Detalles Bibliográficos
Autores principales: Frumkin, Idan, Yofe, Ido, Bar-Ziv, Raz, Gurvich, Yonat, Lu, Yen-Yun, Voichek, Yoav, Towers, Ruth, Schirman, Dvir, Krebber, Heike, Pilpel, Yitzhak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728054/
https://www.ncbi.nlm.nih.gov/pubmed/31442222
http://dx.doi.org/10.1371/journal.pbio.3000423

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