Cargando…
Continuous evolution of base editors with expanded target compatibility and improved activity
Autores principales: | Thuronyi, Benjamin W., Koblan, Luke W., Levy, Jonathan M., Yeh, Wei-Hsi, Zheng, Christine, Newby, Gregory A., Wilson, Christopher, Bhaumik, Mantu, Shubina-Oleinik, Olga, Holt, Jeffrey R., Liu, David R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728210/ https://www.ncbi.nlm.nih.gov/pubmed/31332326 http://dx.doi.org/10.1038/s41587-019-0193-0 |
Ejemplares similares
-
Phage-assisted evolution of an adenine base editor with improved Cas domain compatibility and activity
por: Richter, Michelle F., et al.
Publicado: (2020) -
Improving cytidine and adenine base editors by expression optimization and ancestral reconstruction
por: Koblan, Luke W., et al.
Publicado: (2018) -
Optimized AAV Vectors for TMC1 Gene Therapy in a Humanized Mouse Model of DFNB7/11
por: Marcovich, Irina, et al.
Publicado: (2022) -
Continuous evolution of SpCas9 variants compatible with non-G PAMs
por: Miller, Shannon M., et al.
Publicado: (2020) -
Phage-Assisted Continuous Evolution (PACE): A Guide
Focused on Evolving Protein–DNA Interactions
por: Popa, Serban C., et al.
Publicado: (2020)