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Fatty acids and cancer-amplified ZDHHC19 promote STAT3 activation through S-Palmitoylation

Signal transducer and activator of transcription 3 (STAT3) plays a critical role in regulating cell fate, inflammation and immunity(1,2). Cytokines and growth factors activate STAT3 through kinase-mediated tyrosine phosphorylation and dimerization(3,4). It remains unknown whether other factors could...

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Detalles Bibliográficos
Autores principales:	Niu, Jixiao, Sun, Yang, Chen, Baoen, Zheng, Baohui, Jarugumilli, Gopala K., Walker, Sarah R., Hata, Aaron N., Mino-Kenudson, Mari, Frank, David A., Wu, Xu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728214/ https://www.ncbi.nlm.nih.gov/pubmed/31462771 http://dx.doi.org/10.1038/s41586-019-1511-x

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