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Demographic, laboratory findings and diagnostic evaluation among high risk patients with mucopolysaccharidosis in Malaysia

This article contains information related to a recent study “Selective screening for detection of mucopolysaccharidoses (MPS) in Malaysia; A Two-year Study” Affandi et al., 2019. Any patient registered under government healthcare facilities in Malaysia and fit at least two inclusion criteria were in...

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Autores principales: Omar, Affandi, Jalil, Julaina A., Shakrin, Norashareena M., Ngu, Lock H., Yunus, Zabedah M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728261/
https://www.ncbi.nlm.nih.gov/pubmed/31516928
http://dx.doi.org/10.1016/j.dib.2019.104377
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author Omar, Affandi
Jalil, Julaina A.
Shakrin, Norashareena M.
Ngu, Lock H.
Yunus, Zabedah M.
author_facet Omar, Affandi
Jalil, Julaina A.
Shakrin, Norashareena M.
Ngu, Lock H.
Yunus, Zabedah M.
author_sort Omar, Affandi
collection PubMed
description This article contains information related to a recent study “Selective screening for detection of mucopolysaccharidoses (MPS) in Malaysia; A Two-year Study” Affandi et al., 2019. Any patient registered under government healthcare facilities in Malaysia and fit at least two inclusion criteria were included in this selective screening. Urine and blood from these high risk patients were obtained and analysed for glycosaminoglycans (GAGs) level before characterization using high resolution electrophoresis (HRE). Thereafter, enzyme assay for different types of MPS based on result of HRE were determined using specific substrate. Demographic data as well as laboratory findings were tabulated and analysed. The data of this study demonstrate between clinical presentation and laboratory findings among high risk patients of MPS and can be employed to improve diagnosis of MPS.
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spelling pubmed-67282612019-09-12 Demographic, laboratory findings and diagnostic evaluation among high risk patients with mucopolysaccharidosis in Malaysia Omar, Affandi Jalil, Julaina A. Shakrin, Norashareena M. Ngu, Lock H. Yunus, Zabedah M. Data Brief Biochemistry, Genetics and Molecular Biology This article contains information related to a recent study “Selective screening for detection of mucopolysaccharidoses (MPS) in Malaysia; A Two-year Study” Affandi et al., 2019. Any patient registered under government healthcare facilities in Malaysia and fit at least two inclusion criteria were included in this selective screening. Urine and blood from these high risk patients were obtained and analysed for glycosaminoglycans (GAGs) level before characterization using high resolution electrophoresis (HRE). Thereafter, enzyme assay for different types of MPS based on result of HRE were determined using specific substrate. Demographic data as well as laboratory findings were tabulated and analysed. The data of this study demonstrate between clinical presentation and laboratory findings among high risk patients of MPS and can be employed to improve diagnosis of MPS. Elsevier 2019-08-09 /pmc/articles/PMC6728261/ /pubmed/31516928 http://dx.doi.org/10.1016/j.dib.2019.104377 Text en © 2019 The Author(s) http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Biochemistry, Genetics and Molecular Biology
Omar, Affandi
Jalil, Julaina A.
Shakrin, Norashareena M.
Ngu, Lock H.
Yunus, Zabedah M.
Demographic, laboratory findings and diagnostic evaluation among high risk patients with mucopolysaccharidosis in Malaysia
title Demographic, laboratory findings and diagnostic evaluation among high risk patients with mucopolysaccharidosis in Malaysia
title_full Demographic, laboratory findings and diagnostic evaluation among high risk patients with mucopolysaccharidosis in Malaysia
title_fullStr Demographic, laboratory findings and diagnostic evaluation among high risk patients with mucopolysaccharidosis in Malaysia
title_full_unstemmed Demographic, laboratory findings and diagnostic evaluation among high risk patients with mucopolysaccharidosis in Malaysia
title_short Demographic, laboratory findings and diagnostic evaluation among high risk patients with mucopolysaccharidosis in Malaysia
title_sort demographic, laboratory findings and diagnostic evaluation among high risk patients with mucopolysaccharidosis in malaysia
topic Biochemistry, Genetics and Molecular Biology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728261/
https://www.ncbi.nlm.nih.gov/pubmed/31516928
http://dx.doi.org/10.1016/j.dib.2019.104377
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