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Electrophysiological evaluation of extracellular spermine and alkaline pH on synaptic human GABA(A) receptors

Polyamines have fundamental roles in brain homeostasis as key modulators of cellular excitability. Several studies have suggested alterations in polyamine metabolism in stress related disorders, suicide, depression, and neurodegeneration, making the pharmacological modulation of polyamines a highly...

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Detalles Bibliográficos
Autores principales: Limon, A., Delbruck, E., Yassine, A., Pandya, D., Myers, R. M., Barchas, J. D., Lee, F., Schatzberg, Watson, S. J., Akil, H., Bunney, W. E., Vawter, M. P., Sequeira, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728327/
https://www.ncbi.nlm.nih.gov/pubmed/31488811
http://dx.doi.org/10.1038/s41398-019-0551-1