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Electrophysiological evaluation of extracellular spermine and alkaline pH on synaptic human GABA(A) receptors
Polyamines have fundamental roles in brain homeostasis as key modulators of cellular excitability. Several studies have suggested alterations in polyamine metabolism in stress related disorders, suicide, depression, and neurodegeneration, making the pharmacological modulation of polyamines a highly...
Autores principales: | Limon, A., Delbruck, E., Yassine, A., Pandya, D., Myers, R. M., Barchas, J. D., Lee, F., Schatzberg, Watson, S. J., Akil, H., Bunney, W. E., Vawter, M. P., Sequeira, A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728327/ https://www.ncbi.nlm.nih.gov/pubmed/31488811 http://dx.doi.org/10.1038/s41398-019-0551-1 |
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