A general strategy for diversifying complex natural products to polycyclic scaffolds with medium-sized rings

The interrogation of complex biological pathways demands diverse small molecule tool compounds, which can often lead to important therapeutics for the treatment of human diseases. Since natural products are the most valuable source for the discovery of therapeutics, the derivatization of natural pro...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Changgui, Ye, Zhengqing, Ma, Zhi-xiong, Wildman, Scott A., Blaszczyk, Stephanie A., Hu, Lihong, Guizei, Ilia A., Tang, Weiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728360/
https://www.ncbi.nlm.nih.gov/pubmed/31488839
http://dx.doi.org/10.1038/s41467-019-11976-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728360/
https://www.ncbi.nlm.nih.gov/pubmed/31488839
http://dx.doi.org/10.1038/s41467-019-11976-2

Ejemplares similares