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A general strategy for diversifying complex natural products to polycyclic scaffolds with medium-sized rings
The interrogation of complex biological pathways demands diverse small molecule tool compounds, which can often lead to important therapeutics for the treatment of human diseases. Since natural products are the most valuable source for the discovery of therapeutics, the derivatization of natural pro...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6728360/ https://www.ncbi.nlm.nih.gov/pubmed/31488839 http://dx.doi.org/10.1038/s41467-019-11976-2 |